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Jul 21, 2026Structural snapshots reveal how the plant KCS6-CER2 complex drives very-long-chain fatty acid elongationResearchers from the Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences (GIBH, CAS), together with collaborators, have uncovered the molecular mechanism by which the plant-specific KCS6-CER2 enzyme complex cataly...Researchers from the Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences (GIBH, CAS), together with collaborators, have uncovered the molecular mechanism by which the plant-specific KCS6-CER2 enzyme complex cataly... -
Jul 21, 2026Researchers have developed two PROTAC degraders which target BRD9 for combating malignanciesA research team from the Intelligent Drug Design Research Group at the Guangzhou Institutes of Biomedicine and Health (GIBH) of the Chinese Academy of Sciences has made significant progress in the development of anticancer agents targeti...A research team from the Intelligent Drug Design Research Group at the Guangzhou Institutes of Biomedicine and Health (GIBH) of the Chinese Academy of Sciences has made significant progress in the development of anticancer agents targeti... -
Jun 05, 2026Researchers Uncover How ERDRP-0519 Differentially Targets Morbillivirus and Henipavirus Polymerases, Enabling Structure-Guided Inhibitor OptimizationA research team from the Guangzhou Institutes of Biomedicine and Health (GIBH) of the Chinese Academy of Sciences, together with collaborators from Shandong University, Wuhan Institute of Virology, Guangzhou Laboratory and Guangzhou Medi...A research team from the Guangzhou Institutes of Biomedicine and Health (GIBH) of the Chinese Academy of Sciences, together with collaborators from Shandong University, Wuhan Institute of Virology, Guangzhou Laboratory and Guangzhou Medi... -
Apr 08, 2026Researchers reveal a cell-fate "rheostat" governing somatic reprogrammingA recent study from Professor LIU Jing’s team at the Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences (GIBH, CAS), was published online in Stem Cell Reports as “Dose-Resolved Control of Somatic Reprogramming ...A recent study from Professor LIU Jing’s team at the Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences (GIBH, CAS), was published online in Stem Cell Reports as “Dose-Resolved Control of Somatic Reprogramming ... -
Apr 03, 2026GIBH Collaborates to Develop Selective DNMT1 Inhibitors for Hypomethylating Agent-Resistant Acute Myeloid LeukemiaA collaborative team from the Guangzhou Institutes of Biomedicine and Health (GIBH), Chinese Academy of Sciences, Johns Hopkins University, and the Hangzhou Institute for Advanced Study recently published a study in PNAS entitled Structu...A collaborative team from the Guangzhou Institutes of Biomedicine and Health (GIBH), Chinese Academy of Sciences, Johns Hopkins University, and the Hangzhou Institute for Advanced Study recently published a study in PNAS entitled Structu... -
Mar 20, 2026Researchers develop a mitochondrial transplantation approach for mitochondrial and degenerative diseasesMitochondria, the powerhouse of cells, are essential for human health. Mitochondrial dysfunction underlies numerous major diseases, including neurodegenerative diseases, diabetes, hepatic diseases, ophthalmic diseases, and aging. Mitocho...A recent study from LIU Xinguo’s group was published in Cell entitled “Transplantation of encapsulated mitochondria alleviates dysfunction in mitochondrial and Parkinson's disease models”.Mitochondria, the powerhouse of cells, are ess...