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Jul 11, 2024GIBH Develope a New Tool CACIMAR for Analyzing Cross-Species Single-Cell Sequencing DataRecently, WANG Jie's research group from the Guangzhou Institutes of Biomedicine and Health (GIBH), the Chinese Academy of Sciences, developed a new computational tool named CACIMAR (Cross-species Analysis of Cell Identities, Markers, Re...Recently, WANG Jie's research group from the Guangzhou Institutes of Biomedicine and Health (GIBH), the Chinese Academy of Sciences, developed a new computational tool named CACIMAR (Cross-species Analysis of Cell Identities, Markers, Re... -
Jul 11, 2024Researchers Uncover Novel Mechanism Regulating GPCR-G Protein Signaling from EndosomesRecently, researchers from Guangzhou Institutes of Biomedicine and Health (GIBH) of Chinese Academy of Sciences published a paper entitled "Redox-Modulated SNX25 as a Novel Regulator of GPCR-G Protein Signaling from Endosomes" in Redox B...G Protein-Coupled Receptors (GPCRs) were traditionally believed to be activated solely on the plasma membrane, becoming desensitized post-internalization. However, increasing evidence suggestes that some internalized GPCRs retain their a... -
May 15, 2024Mitochondrial DNA-encoded 14th Protein Discovered from Cytosolic TranslationMitochondria are multifunctional organelles that provide energy for multiple cellular activities, but are also indispensable for apoptosis regulation, cell signaling and many biosynthetic pathways. Many of these functions entail the re... -
Apr 26, 2024Researchers Make New Progress in Studying Automated Monoclonal Lineage Cells Selecting TechnologyDespite the broad prospects for the application of lineage-specific cells in regenerative medicine, traditional methods for obtaining monoclonal lineage cells through manual manipulation are time-consuming, labor-intensive, and generally...Despite the broad prospects for the application of lineage-specific cells in regenerative medicine, traditional methods for obtaining monoclonal lineage cells through manual manipulation are time-consuming, labor-intensive, and generally... -
Mar 19, 2024GIBH Uncover a Novel HBO1 Mechanism Influencing SMAD Function in the Regulation of Pluripotency and Mesendoderm SpecificationThe research titled "HBO1 determines SMAD action in pluripotency and mesendoderm specification" was published in the journal Nucleic Acids Research by PAN Guangjin’s research group from the Guangzhou Institutes of Biomedicine and Health...The research titled "HBO1 determines SMAD action in pluripotency and mesendoderm specification" was published in the journal Nucleic Acids Research by PAN Guangjin’s research group from the Guangzhou Institutes of Biomedicine and Health... -
Mar 19, 2024GIBH Progresses in Anti-tumor Research and Development of Genetically Engineered Macrophages Derived from Human Pluripotent Stem CellsRecently, PAN Guangjin's team from Guangzhou Institutes of Biomedicine and Health(GIBH) of Chinese Academy of Sciences published a paper entitled "Large-scale generation of IL-12 secreting macrophages from human pluripotent stem cells fo...Recently, PAN Guangjin's team from Guangzhou Institutes of Biomedicine and Health(GIBH) of Chinese Academy of Sciences published a paper entitled "Large-scale generation of IL-12 secreting macrophages from human pluripotent stem cells fo...