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Sep 26, 2023GIBH Uncovers Novel Mechanism by Which BCL11B and NuRD Complex Cooperatively Maintain T-cell FateAdoptive cell therapy, particularly CAR-T and CAR-NK cell therapies, has emerged as a promising approach for cancer immunotherapy. These therapies have demonstrated remarkable success in treating hematologic malignancies. However, no CAR... -
Sep 19, 2023GIBH Reveals How MARCH7 Regulates Autophagy via Ubiquitinating ATG14Recently, the team led by Dr. ZHANG Xiaofei from the Guangzhou Institutes of Biomedicine and Health of the Chinese Academy of Sciences, published a research paper titled "MARCH7-Mediated Ubiquitination Decreases the Solubility of ATG14 t... -
Sep 15, 2023GIBH Develops a Downstream Analysis and Visualization Tool for Quantitative Proteomic DataQuantitative proteomics based on high-performance liquid chromatography-mass spectrometry (HPLC-MS) has emerged as an important tool in life science research. Like other omics methodologies, a well-defined and systematic data analysis wo... -
Sep 12, 2023Researchers Grow Humanized Mesonephros Inside Pig Embryos for 28 DaysOn September 7th, LAI Liangxue’s group, PAN Guangjin’s group and Miguel A. Esteban’s group from Guangzhou Institutes of Biomedicine and Health (GIBH) of Chinese Academy of Sciences (CAS) published a cover paper together in the world's...On September 7th, LAI Liangxue’s group, PAN Guangjin’s group and Miguel A. Esteban’s group from Guangzhou Institutes of Biomedicine and Health (GIBH) of Chinese Academy of Sciences (CAS) published a cover paper together in the world's... -
Aug 04, 2023Novel Vaccine Effectively Prevents Infection of African Swine Fever VirusAfrican Swine Fever Virus (ASFV) infection poses a serious threat to the global pig industry. It is listed as a reportable animal disease by the World Organization for Animal Health and categorized as a Class A zoonosis by Chinese gove... -
Jul 20, 2023Researchers Develop Switchable CAR-T for Tumor -associated AntigensCAR-T therapy has achieved good results in treating hematologic malignancies, but it shows limited efficacy in solid tumors. Traditional CAR-T only targets one or two antigen epitopes. However, cancer cells are prone to loss antigens, en...CAR-T therapy has achieved good results in treating hematologic malignancies, but it shows limited efficacy in solid tumors. Traditional CAR-T only targets one or two antigen epitopes. However, cancer cells are prone to loss antigens, en...