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Mar 15, 2022Study: Artery Regulates Colonization of Hematopoietic Stem/Progenitor Cells in Embryonic Bone MarrowHematopoietic stem cells (HSCs) have been transplanted for treating malignant blood disorders after radiotherapy and chemotherapy because of their capability to differentiate into any type of specialized blood cells. The knowledge regard... -
Mar 08, 2022scDIOR Bridges Platforms of R and Python for Single-cell Data TransformationPrinciple Investigator CHEN Jiekai’s group of Guangzhou Institutes of Biomedicine and Health (GIBH) of the Chinese Academy of Sciences has developed a software scDIOR for the single-cell data transformation between platforms of R and Py... -
Jan 14, 2022Physical Exercise Boosts Maturation of Transplanted Neurons and Recovery in Stroke ModelStroke is a leading cause of death and disability worldwide. The key to treat stroke is to functionally replace the dead neurons in the brain. Therefore, transplantation of neural progenitor cells(NPCs) is considered as a promising appro... -
Jan 13, 2022B cell regeneration from pluripotent stem cellsB cells are essential for a functional and complete humoral immune system. With certain disease conditions, the B lymphopoiesis and serum immunoglobulin levels are severely impaired, resulting in infections in patients. Regeneration of a... -
Dec 20, 2021NMPA Approved the First New Drug Independently Discovered by GIBHOn November 25th, Olverembatinib developed independently by Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences (referred to as GIBH hereinafter) was officially approved t by the National Medical Products Adminis... -
Nov 29, 2021Scientists reveal a progressive modification mode of heterochromatin relaxation by kinaseCompared with somatic cells, pluripotent stem cells have an open chromatin state and less heterochromatin. The transition between heterochromatin and euchromatin is the key in cell fate determination, including somatic cell reprogramming...