-
May 26, 2023Novel Spatial Multi-omics Technology Deciphers Spatiotemporal Lineage of Mouse Brain DevelopmentHuman and many other mammals are composed of billions of cells, which, although originating from the same fertilized egg, differ in types, developmental timing, and spatial distribution. But how are the identity and function of these cel...Human and many other mammals are composed of billions of cells, which, although originating from the same fertilized egg, differ in types, developmental timing, and spatial distribution. But how are the identity and function of these cel... -
Jan 12, 2023Researchers Develop Highly Sensitive and Specific CRISPR/Cas12a-based Detection Method for Helicobacter PyloriProf. LI Zhiyuan’s group at Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences proposed a novel method for the ultrasensitive and specific detection of the highly pathogenic helicobacter pylori (H. pylori) strai...Prof. LI Zhiyuan’s group at Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences proposed a novel method for the ultrasensitive and specific detection of the highly pathogenic helicobacter pylori (H. pylori) strai... -
Jun 06, 2022New Base Editing System Developed for Creating Saturated Mutant PopulationsRecently, LAI Liangxue’s Lab from Guangzhou Institute of Biomedicine and Health (GIBH) of Chinese Academy of Sciences (CAS) has developed a new type of dual deaminase-mediated base editing system, the AGBE system. It can widely induce m... -
Apr 20, 2022Mitolysosome Exocytosis, a Novel Mechanism Helps to Unveil Drug-induced ParkinsonismAs the second most common cause of parkinsonism following Parkinson’s disease, drug-induced parkinsonism is affecting people’s life and health particularly in an aging society. Chronic use of flunarizine (FNZ), a drug often for treatin... -
Apr 18, 2022Researchers First Obtain Functional Human Blood Cells via Interspecies ChimerismInterspecies chimerism is a phenomenon of an organism consisting of tissue and genetic information from two different species. Currently, many researchers look into the use of interspecies chimerism with human pluripotent stem cells (hPS... -
Apr 02, 2022Researchers develop a novel gene base editor free of Cas9-dependent off-targetingRecently, Prof. LAI Liangxue from Guangzhou Institutes of Biomedicine and Health (GIBH) of Chinese Academy of Sciences collaborating with Dr. ZOU Qingjian from Wuyi University, has developed a novel base editing system, TaC9-ABE, which i...