-
Jan 18, 2024Researchers Discover Highly Selective BET BD2 Inhibitors for the Treatment of AMLRecently, the research group led by Prof. Xu Yong at Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences (GIBH, CAS), in collaboration with Prof. Wu Xiaoxing 's group at the China Pharmaceutical University (CPU), ...Recently, the research group led by Prof. Xu Yong at Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences (GIBH, CAS), in collaboration with Prof. Wu Xiaoxing 's group at the China Pharmaceutical University (CPU), ... -
Jan 18, 2024Researchers reveal a novel mechanism by which Autophagy regulates the expansion of human myeloid progenitorsIn a study published in Stem Cell Reports, the team led by Prof. PAN Guangjin from Guangzhou Institutes of Biomedicine and Health of the Chinese Academy of Science (GIBH, CAS), revealed a novel mechanism by which ATG7-dependent autophagy...In a study published in Stem Cell Reports, the team led by Prof. PAN Guangjin from Guangzhou Institutes of Biomedicine and Health of the Chinese Academy of Science (GIBH, CAS), revealed a novel mechanism by which ATG7-dependent autophagy... -
Dec 20, 2023Researchers Uncover New Mechanisms of Vitamin C in Regulating Somatic Cell ReprogrammingRecently, the team led by Dr. ZHENG Hui from the Guangzhou Institutes of Biomedicine and Health (GIBH), Chinese Academy of Sciences (CAS), published an article titled “Unraveling the 2,3-diketo-L-gulonic acid-dependent and -independent ...L-Ascorbic acid (Asc), commonly known as Vitamin C (Vc), is an essential nutrient that plays a crucial role in many physiological processes. Previous studies have shown that Vc improves the efficiency of somatic cell reprogramming throug... -
Nov 14, 2023Researchers Generate Live-birth Chimeric Monkey Using Embryonic Stem CellsOn Nov. 9, a study was published online in Cell entitled “Live birth of chimeric monkey with high contribution from embryonic stem cells”. This work reported the generation of a live-birth chimeric monkey containing high contribution o...On Nov. 9, a study was published online in Cell entitled “Live birth of chimeric monkey with high contribution from embryonic stem cells”. This work reported the generation of a live-birth chimeric monkey containing high contribution o... -
Sep 26, 2023GIBH Uncovers Novel Mechanism by Which BCL11B and NuRD Complex Cooperatively Maintain T-cell FateAdoptive cell therapy, particularly CAR-T and CAR-NK cell therapies, has emerged as a promising approach for cancer immunotherapy. These therapies have demonstrated remarkable success in treating hematologic malignancies. However, no CAR... -
Sep 19, 2023GIBH Reveals How MARCH7 Regulates Autophagy via Ubiquitinating ATG14Recently, the team led by Dr. ZHANG Xiaofei from the Guangzhou Institutes of Biomedicine and Health of the Chinese Academy of Sciences, published a research paper titled "MARCH7-Mediated Ubiquitination Decreases the Solubility of ATG14 t...