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Feb 18, 2025The research team of GIBH discovered the target gene Lhx2 in hepatic stellate cells regulating liver regeneration and fibrosisRecently, the research teams of WANG Jie and LI Yinxiong from the Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences (GIBH, CAS), in collaboration with YUAN Shengxian's team from the Eastern Hepatobiliary Surgery... -
Feb 17, 2025Researchers Unlock Guinea Pig Epiblast Stem CellsSince the advent of pluripotent stem cell (PSC) technology, researchers have continually advanced methods to refine efficiency, improve safety, and uncover novel biological insights. While guinea pigs have historically played a vital rol... -
Feb 17, 2025International Collaboration Uncovered Potential Therapeutic Strategies for Solid Tumors by Targeting UHRF1 for DNA DemethylationA recent study, led by Dr. KONG Xiangqian, Dr. LIU Jinsong, and Dr. WU Linping's labs at the Guangzhou Institutes of Biomedicine and Health (GIBH), Chinese Academy of Sciences (CAS), in collaboration with Dr. Stephen Baylin's group at Th... -
Jan 26, 2025Researchers developed a novel method for SALL4-mediated somatic cell reprogrammingRecently, Prof. LIU Jing from Guangzhou Institutes of Biomedicine and Health (GIBH), Chinese Academy of Sciences, in collaboration with Prof. LIAO Baojian of the Fifth Affiliated Hospital of Guangzhou Medical University, published an art...Recently, Prof. LIU Jing from Guangzhou Institutes of Biomedicine and Health (GIBH), Chinese Academy of Sciences, in collaboration with Prof. LIAO Baojian of the Fifth Affiliated Hospital of Guangzhou Medical University, published an art... -
Aug 08, 2024MSC-Mediated Mitochondrial Transfer Restores Mitochondrial DNA and Function in Neural Progenitor Cells of Leber's Hereditary Optic NeuropathyThe results suggest that MSCs can transfer functional mitochondria to neural progenitor cells, thus restoring their function and potentially offering a new therapeutic strategy for mitochondrial diseases.Researchersled byProf. LIU Xingguo fromGuangzhou Institutes of Biomedicine and Healthof Chinese Academy of Sciences and Prof. ZHANG QingjiongfromZhongshan Ophthalmic Centerhave discovered that that MSC-mediated mitochondrial transfer can... -
Jul 30, 2024Mechanisms of Aging Associated Protein Translation Deficiency DiscoveredThe study discovered that METTL1/WDR4-mediated tRNA-m7G methylationwas essential in the preservation of proteostasis in healthy cells, which play an important role in the prevention of premature aging.The teams led by Prof. WANG Tao and Prof. WANG Jie from GIBH collaborated to identify novel mechanisms for regulating aging. The finding was published in Nature Communications with the title "Perturbation of METTL1-mediated tRNA N7-methy...