A new chapter in history has begun with the arrival of the optimistic year 2024. I would like to extend my sincere wishes, on behalf of the Guangzhou Institutes of Biomedicine and Health (GIBH), Chinese Academy of Sciences (CAS), to all the staff, students, retired colleagues, and friends from all walks of life who care about and support the development of GIBH at this wonderful moment of bidding farewell to the old and welcoming the new. Happy New Year!
2023 is a year of great significance for the development of the Party. It marks the beginning of implementing the spirit of the 20th National Congress of the Communist Party of China. It is also a crucial year for carrying out theme education, consolidating cohesion, focusing on main responsibilities and businesses, and implementing the 14th Five-Year Plan. Furthermore, 2023 lays the foundation for the comprehensive construction of a socialist modernized country.
2023 is a milestone year for GIBH. We are eagerly welcoming our 20th birthday. Looking back, we have made breakthrough achievements in scientific research, talent team building, major achievement output, graduate training, domestic and international cooperation, Party building and innovative culture, social services, and other aspects.
Over the past year, we have diligently implemented the spirit of the 20th National Congress of the Communist Party of China, with a primary focus on seizing the scientific high ground. Following the general guideline of "focusing on layout, reshaping the team, and improving efficiency", and adhering to the main line of "strengthening the foundation, tackling key problems, gathering talents, and promoting reform", we will continue to implement our tasks to a new level.
We are delighted to see our independently developed original Class 1 new drug, Olverembatinib, in the national medical insurance catalog. This breakthrough overcomes the issue of T315I mutant-resistant patients in China being without treatment and we are committed to safeguarding people’s lives and health. Additionally, in collaboration with the Malaghan Institute of Medical Research in New Zealand, we conducted a phase II clinical trial of CAR-T cell treatment for B-cell lymphoma. This was the first CAR-T cell technology introduced in New Zealand and the first CAR-T cell clinical trial that was approved. Moreover, after a decade-long collaboration with the Maurice Wilkins Research Center, the targeted anti-tumor new drug, LX-132 Capsule, which was co-developed by our institute, has received clinical approval as a Category 1 new drug from the National Medical Products Administration.
GIBH and CAS research team collaboratively achieved the xenotransplantation of humanized kidneys within a porcine model, representing the world's first reported case of intraspecies organ generation. This groundbreaking accomplishment has been acknowledged by the esteemed journal "Science" as a "pioneering advancement and milestone event in the field of organ transplantation and regeneration." Additionally, we initiated the first international collaboration to generate chimeric monkeys with a substantial contribution from embryonic stem cells, confirming the efficient contribution of monkey embryonic stem cells into extra-embryonic placental tissues and germ cells. This achievement has had a significant impact on both the national and international levels.
GIBH takes charge of the establishment of the Human Cell Lineage Atlas Facility (CLAF), a major national science and technology infrastructure project in the 14th Five-Year Plan period. The National Development and Reform Commission has approved the feasibility report.
These achievements are attributed to the unwavering determination and commitment of every member of GIBH. They are the outcome of our steadfast adherence to the directives set forth by the Central Committee of the Communist Party of China, as well as the strong support received from Guangdong Province, Guangzhou City, and the Guangzhou Development Zone.
Looking back on 2023, we embraced opportunities, tackled key issues, and propelled development, symbolizing the beginning of a new era for high-quality progress for the next two decades. The journey ahead will undoubtedly come with challenges, but it will also yield fruitful outcomes, reminding us that dreams materialize through practical actions, excellence is shaped through reforms and a prosperous future is achieved through diligent efforts.
Looking ahead to 2024, we acknowledge the immense strategic significance of seizing the commanding heights of science and technology. This pursuit is crucial for achieving self-reliance and self-sufficiency in advanced scientific and technological endeavors, and it holds profound historical significance for the reform, innovation, and development of Chinese Academy of Sciences. We recognize the series of major practical challenges that lie in attaining technological superiority. This realization further strengthens our sense of mission and responsibility, instilling in us a willingness to make sacrifices, bear heavy burdens, and embrace a sense of urgency to seize every moment. With these principles in mind, we will effectively fulfil our responsibilities and missions as key national strategic scientific and technological forces. Let us forge ahead and set sail once again on this remarkable journey!
"As the East brightens, do not say the journey is early. After traversing the green mountains, one is not old; the scenery on this side is exceptionally good." Let us unite closely around the Party Central Committee, with Comrade President Xi at its core. Let us deeply comprehend the decisive significance of "two establishing," enhance our "four consciousnesses," strengthen our "four confidences," and uphold the principle of "two safeguards." By accelerating the seizure of scientific and technological heights to lead the overall situation, consolidating strength, forging ahead, and focusing on the implementation of the science and technology commanding heights tasks, let us work with a sense of mission, shoulder heavy responsibilities, and seize the moment. Dreams can be fulfilled through practical work, brilliance can be written through reforms, future can be won through efforts.
The bright future is unfolding, and a splendid chapter is being written. May our beloved motherland thrive and prosper! May our noble cause flourish with each passing day, and may the dream of a community of shared human destiny for health can come true soon!
Party Secretary, Duan Ziyuan