Research Progress
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Jan 14, 2021Important Progress in Generation of Hematopoietic Stem/Progenitor Cells in vitroRecently, Pan Guangjin's research team in the Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences reported important progress in generation of multi-potent hematopoietic stem/progenitor cells from human pluripotent...
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Oct 13, 2020Scientists reveal the cooperative function of JMJD3 and KLF4 in somatic reprogrammingTen years ago, PEI Duanqing, Miguel A. Esteban, WANG Tao, QIN Baoming and other team members--reported that vitamin C (Vc) greatly boosts the efficiency of both mouse and human somatic cell reprogramming. They demonstrated that Vc inhibi...
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Sep 09, 2020Scientists reveal function of RNA m6A readers during somatic reprogrammingOn September 8, Cell Reports journal published a latest research titled “YTHDF2/3 are required for somatic reprogramming through different RNA deadenylation pathways” from Jiekai Chen’s group in Guangzhou Institute of Biomedicine and ...
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Sep 07, 2020Progress in research of CTCF-mediated chromatin loop in Guangzhou Institute of Biomedicine and HealthOn September 4, Prof. Yao Hongjie, Guangzhou Institute of Biomedicine and Health (GIBH), Chinese Academy of Sciences (CAS), published their research results in the international academic journal Nucleic Acids Research. CTCF is a critica...
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Aug 27, 2020Novel principles of blood cell emergence in humans are revealedLaboratory of Prof. Igor Samokhvalov has recently published in Haematologica (Haematologica; doi:10.3324/haematol.2020.249193) the article “MYB bi-allelic targeting abrogates primitive clonogenic progenitors while the emergence of primi...
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Aug 25, 2020Scientists Reveal an epigenome-metabolome-epigenome signalling cascade mediated by Glis1 facilitating pluripotency inductionOn August 24, Nature Metabolism journal published a latest research titled “Glis1 facilitates induction of pluripotency via an epigenome–metabolome–epigenome signalling cascade” from Xingguo Liu’s group in Guangzhou Institute of Bio...