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Feb 03, 2021Treating HBV-related HCC by affinity-improved-TCR-TThe T-cell receptor engineered T cell therapy (TCR-T) is becoming a promising treatment for cancer, with many TCR-T clinical trials being carried out for treating solid tumors. TCR-T cells engineered with a wild-type TCR, whose natural a... -
Jan 21, 2021New Mechanism of HSC Homeostasis Regulation RevealedWang Jinyong's research team from the Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, and Cheng Hui/Cheng Tao's research team from the State Key Laboratory of Experimental Hematology, Institute of Hematology,... -
Jan 19, 2021Researchers Successfully Established the World's First Pig Model with Systemic Spontaneous Inflammatory ResponsesOn 1st November, Lai Liangxue’s research team from the Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Xiao Lei’s research team from the Zhejiang University, and Meng Guangxun’s research team from the Inst... -
Jan 14, 2021Important Progress in Generation of Hematopoietic Stem/Progenitor Cells in vitroRecently, Pan Guangjin's research team in the Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences reported important progress in generation of multi-potent hematopoietic stem/progenitor cells from human pluripotent... -
Oct 13, 2020Scientists reveal the cooperative function of JMJD3 and KLF4 in somatic reprogrammingTen years ago, PEI Duanqing, Miguel A. Esteban, WANG Tao, QIN Baoming and other team members--reported that vitamin C (Vc) greatly boosts the efficiency of both mouse and human somatic cell reprogramming. They demonstrated that Vc inhibi... -
Sep 09, 2020Scientists reveal function of RNA m6A readers during somatic reprogrammingOn September 8, Cell Reports journal published a latest research titled “YTHDF2/3 are required for somatic reprogramming through different RNA deadenylation pathways” from Jiekai Chen’s group in Guangzhou Institute of Biomedicine and ...