Scientific Publications
| Title | Aouther | Year | Kw |
|---|---|---|---|
| Cre-dependent Cas9-expressing pigs enable efficient in vivo genome editing | Kepin Wang, Qin Jin, Degong Ruan, Yi Yang, Qishuai Liu, Han Wu, Zhiwei Zhou, Zhen Ouyang, Zhaoming Liu, Yu Zhao, Bentian Zhao, Quanjun Zhang, Jiangyun Peng, Chengdan Lai, Nana Fan, Yanhui Liang, Ting Lan, Nan Li, Xiaoshan Wang, Xinlu Wang, Yong Fan, Pieter A. Doevendans, Joost P.G. Sluijter, Pentao Liu, Xiaoping Li,Liangxue La |
2017 Dec; | Genome Research |
| SNX16 Regulates the Recycling of E-Cadherin through a Unique Mechanism of Coordinated Membrane and Cargo Binding | Jinxin Xu, Leilei Zhang, Yinghua Ye,Yongli Shan,Chanjuan Wan,Junfeng Wang,Duanqing Pei, Xiaodong Shu,Jinsong Liu |
2017 Aug; | Structure |
| Plasmodium parasite as an effective hepatocellular carcinoma antigen glypican-3 delivery vector | Quan Liu, Yijun Yang, Xuefang Tan, Zhu Tao, Dickson Adah, Songlin Yu, Junnan Lu, Siting Zhao, Limei Qin, Li Qin, Xiaoping Chen |
2017 Apr; | Oncotarget |
| RNA Helicase DDX5 Inhibits Reprogramming to Pluripotency by miRNA-Based Repression of RYBP and its PRC1-Dependent and -Independent Functions | Huanhuan Li, Ping Lai, Jinping Jia, Yawei Song, Qing Xia, Kaimeng Huang, Na He, Wangfang Ping, Jiayu Chen, Zhongzhou Yang, Jiao Li, Mingze Yao, Xiaotao Dong, Jicheng Zhao, Chunhui Hou, Miguel A. Esteban, Shaorong Gao, Duanqing Pei, Andrew P. Hutchins,Hongjie Yao |
2017 Apr; | Cell Stem Cell |
| Heterogeneity of CD34 and CD38 expression in adult acute B lymphoblastic leukemia cells is reversible and not hierarchically organized | Zhiwu Jiang,Manman Deng,Xinru Wei,Wei Ye,Yiren Xiao,Simiao Lin,Suna Wang,Baiheng Li,Xin Liu,Gong Zhang,Peilong Lai,Jianyu Weng,Donghai Wu, Haijia Chen, Wei Wei, Yuguo Ma, Yangqiu Li, Pentao Liu, Xin Du, Duanqing Pei, Yao Yao, Bing Xu,Peng Li |
2016 Sep | Journal of Hematology & Oncology |
| Pd-Catalyzed C(sp2)-H carbonylation of 2-benzylpyridines for the synthesis of pyridoisoquinolinones | Zeqiang Xie, Shuang Luo,Qiang Zhu |
2016 Oct | Chemical Communications |
| Harmine Induces Adipocyte Thermogenesis through RAC1-MEK-ERK-CHD4 Axis | Tao Nie, Xiaoyan Hui, Liufeng Mao, Baoming Nie, Kuai Li, Wei Sun, Xuefei Gao,Xiaofeng Tang, Yong Xu, Baishan Jiang, Zhengcao Tu, Peng Li, Ke Ding, Weiping Han,Shaoping Zhang, Aimin Xu, Sheng Ding, Pentao Liu, Adam Patterson, Garth Cooper,Donghai Wu |
2016 Nov | Scientific Reports |
| Gadd45a is a heterochromatin relaxer that enhances iPS cell generation | Keshi Chen, Qi Long, Tao Wang, Danyun Zhao, Yanshuang Zhou, Juntao Qi, Yi Wu, Shengbiao Li, Chunlan Chen, Xiaoming Zeng, Jianguo Yang, Zisong Zhou, Weiwen Qin, Xiyin Liu, Yuxing Li, Yingying Li, Xiaofen Huang, Dajiang Qin, Jiekai Chen, Guangjin Pan, Hans R Sch？ler, Guoliang Xu, Xingguo Liu, Duanqing Pei |
2016 Nov | EMBO Reports |
| Generation and Analysis of GATA2w/eGFP Human ESCs Reveal ITGB3/CD61 as a Reliable Marker for Defining Hemogenic Endothelial Cells during Hematopoiesis | Ke Huang, Jiao Gao, Juan Du, Ning Ma, Yanling Zhu, Pengfei Wu,Tian Zhang,Wenqian Wang,Yuhang Li, Qianyu Chen, Andrew Paul Hutchins, Zhongzhou Yang, Yi Zheng,Jian Zhang, Yongli Shan, Xuejia Li, Baojian Liao, Jiajun Liu, Jinyong Wang, Bing Liu,Guangjin Pan |
2016 Nov | Stem Cell Reports |
| Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction.Nucleic Acids Research | Miriam Klaus, Nina Prokoph, Mathias Girbig, Xuecong Wang, Yong-Heng Huang, Yogesh Srivastava, Linlin Hou, Kamesh Narasimhan,
Prasanna R. Kolatkar, Mathias Francois,Ralf Jauch |
2016 May | Nucleic Acids Research |
| Potent neutralizing monoclonal antibodies against Ebola virus infection | Qi Zhang, Miao Gui, Xuefeng Niu, Shihua He, Ruoke Wang, Yupeng Feng, Andrea Kroeker, Yanan Zuo, Hua Wang, Ying Wang, Jiade Li, Chufang Li, Yi Shi, Xuanling Shi, George F. Gao, Ye Xiang, Xiangguo Qiu, Ling Chen,Linqi Zhang |
2016 May | Scientific Reports |
| Simple and versatile synthetic polydopamine-based surface supports reprogramming of human somatic cells and long-term self-renewal of human pluripotent stem cells under defined conditions | Ping Zhou,Fujian Wu, Tiancheng Zhou, Xiujuan Cai, Siqi Zhang, Xiaohong Zhang, Qiuhong Li, Yongliang Li, Yunfei Zheng, Mengke Wang, Feng Lan, Guangjin Pan, Duanqing Pei, Shicheng Wei |
2016 May | Biomaterials |
| Copper-mediated C(sp3)–H azidation with Me3SiN3: synthesis of imidazoles from ketones and aldehydes.Chemical Communications | Zeqiang Xie,Jiaojiao Deng,Zhiping Qiu,Juan Li,Qiang Zhu |
2016 May | Chemical Communications |
| Optimized Approaches for Generation of Integration-free iPSCs from Human Urine-Derived Cells with Small Molecules and Autologous Feeder | Di Li, Linli Wang, Jundi Hou, Qun Shen, Qianyu Chen, Xiaoshan Wang, Juan Du, Xiujuan Cai, Yongli Shan, Tian Zhang, Tiancheng Zhou, Xi Shi, Yuhua Li, Hua Zhang, Guangjin Pan |
2016 May | Stem Cell Reports |
| ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer | Junjian Wang, June X Zou, Xiaoqian Xue, Demin Cai, Yan Zhang, Zhijian Duan, Qiuping Xiang, Joy C Yang, Maggie C Louie, Alexander D Borowsky, Allen C Gao, Christopher P Evans, Kit S Lam1, Jianzhen Xu, Hsing-Jien Kung, Ronald M Evans, Yong Xu, Hong-Wu Chen |
2016 May | Nature Medicine |
| TGFβ signaling regulates the choice between pluripotent and neural fates during reprogramming of human urine derived cells | Lihui Wang, Xirui Li, Wenhao Huang, Tiancheng Zhou, Haitao Wang, Aiping Lin, Andrew Paul Hutchins1, Zhenghui Su, Qianyu Chen, Duanqing Pei, Guangjin Pan |
2016 Mar | Scientific Reports |
| Structure-Based Design of Potent Nicotinamide Phosphoribosyltransferase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities | Jinhong Bai, Chenzhong Liao,Yanghan Liu, Xiaochu Qin, Jiaxuan Chen, Yatao Qiu,Dongguang Qin, Zheng Li,Zheng-Chao Tu,Sheng Jiang |
2016 Jun | Journal of Medicinal Chemistry |
| A metal-free synthesis of 2-aminobenzothiazoles through aminyl radical addition to aryl isothiocyanates | Yimiao He, Jing Li, Shuang Luo, Jinbo Huang,Qiang Zhu |
2016 Jun | Chemical Communications |
| Structure-Based Design of Tetrahydroisoquinoline-7-carboxamides as Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors | Zhen Wang, Huan Bian, Sergio G. Bartual, Wenting Du, Jinfeng Luo, Hu Zhao, Shasha Zhang, Cheng Mo, Yang Zhou, Yong Xu, Zhengchao Tu, Xiaomei Ren, Xiaoyun Lu, Rolf A. Brekken, Libo Yao, Alex N. Bullock, Jin Su, Ke Ding |
2016 Jun | Journal of Medicinal Chemistry |
| GZD824 suppresses the growth of human B cell precursor acute lymphoblastic leukemia cells by inhibiting the SRC kinase and PI3K/AKT pathways | Wei Ye, Zhiwu Jiang, Xiaoyun Lu, Xiaomei Ren, Manman Deng, Shouheng Lin, Yiren Xiao, Simiao Lin, Suna Wang, Baiheng Li, Yi Zheng, Peilong Lai, Jianyu Weng, Donghai Wu, Yuguo Ma, Xudong Chen, Zhesheng Wen, Yaoyu Chen, Xiaoyan Feng, Yangqiu Li, Pentao Liu, Xin Du, Duanqing Pei, Yao Yao, Bing Xu, Ke Ding, Peng Li |
2016 Jul | Oncotarget |
| Intramolecular Imidoylative Heck Reaction: Synthesis of Cyclic Ketoimines from Functionalized Isocyanide | Jian Wang, Shi Tang,Qiang Zhu |
2016 Jul | Organic Letters |
| CRISPR/Cas9-mediated mutation of PHEX in rabbit recapitulates human X-linked hypophosphatemia (XLH) | Tingting Sui1, Lin Yuan1, Huan Liu, Mao Chen, Jichao Deng, Yong Wang, Zhanjun Li, Liangxue Lai |
2016 Jul | Human Molecular Genetics |
| 4-Oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as New Axl Kinase Inhibitors | Li Tan, Zhang Zhang, Donglin Gao, Jinfeng Luo, Zheng-Chao Tu, Zhengqiu Li, Lijie Peng, Xiaomei Ren,Ke Ding |
2016 Jul | Journal of Medicinal Chemistry |
| Conversion of embryonic stem cells into extraembryonic lineages by CRISPR-mediated activators | Shu Wei, Qingjian Zou, Sisi Lai, Quanjun Zhang, Li Li, Quanmei Yan,Xiaoqing Zhou, Huilin Zhong， Liangxue Lai |
2016 Jan | Scientific Reports |
| CRISPR/Cas9 Facilitates Investigation of Neural Circuit Disease using Human iPSCs: Mechanism of Epilepsy Caused by an SCN1A Loss-of-function Mutation | Liu J, Gao C, Chen W, Ma W, Deng S, Li X, Shi Y, Zhang H, Zhang L, Long Y, Xu H, Guo X, Lai L, Pan G, Chen Y, Liao W, Li Z |
2016 Jan | Zhiyuan Li |
| Vaccine Engineering with Dual-Functional Mineral Shell: A Promising Strategy to Overcome Preexisting Immunity | Xiaoyu Wang, Caijun Sun, Pingchao Li, Tongjin Wu, Hangyu Zhou, Dong Yang,Yichu Liu, Xiuchang Ma,Zhiyong Song, Qinggong Nian, Liqiang Feng,Chengfeng Qin, Ling Chen,Ruikang Tang |
2016 Jan | Advanced Materials |
| Srebp-1 Interacts with c-Myc to Enhance Somatic Cell Reprogramming | Yi Wu,Keshi Chen, Xiyin Liu, Lili Huang, Danyun Zhao, Linpeng Li, Mi Gao,Duangqing Pei, Chenguang Wang, Xingguo Liu |
2016 Jan | Stem Cells |
| Transient Activation of Mitoflashes Modulates Nanog at the Early Phase of Somatic Cell Reprogramming | Zhongfu Ying,Keshi Chen,Lingjun Zheng,Yi Wu, Linpeng Li, Rui Wang, Qi Long, Liang Yang, Jingyi Guo, Deyang Yao, Yong Li, Feixiang Bao, Ge Xiang, Jinglei Liu, Qiaoying Huang, Zhiming Wu, Andrew Paul Hutchins,Duanqing Pei, Xingguo Liu |
2016 Jan | Cell Metabolism |
| Portable and quantitative monitoring of mercury ions using DNA-gated mesoporous silica nanoparticles using a glucometer readout | Xiaoling Liang, Lin Wang, Dou Wang, Lingwen Zeng,Zhiyuan Fang |
2016 Feb | Chemical Communications |
| CRISPR/Cas9-mediated GJA8 knockout in rabbits recapitulates human congenital cataracts | Lin Yuan, Tingting Sui, Mao Chen, Jichao Deng, Yongye Huang, Jian Zeng, Qingyan Lv, Yuning Song, Zhanjun Li,Liangxue Lai |
2016 Feb | Scientific Reports |