Scientific Publications
Title Aouther Year Kw
Pluripotency without Proliferation
Xiaodong Shu, Duanqing Pei
2016 Feb
Cell
5-HT2 receptors mediate functional modulation of GABAa receptors and inhibitory synaptictransmissions in human iPS-derived neurons
Haitao Wang, Lingli Hu, Chunhua Liu, Zhenghui Su, Lihui Wang, Guangjin Pan, Yiping Guo, Jufang He
2016 Feb
Scientific Reports
Discovery of Benzo[cd]indol-2(1H)?ones as Potent and Specific BET Bromodomain Inhibitors: Structure-Based Virtual Screening, Optimization, and Biological Evaluation
Xiaoqian Xue, Yan Zhang, Zhaoxuan Liu, Ming Song, Yanli Xing, Qiuping Xiang, Zhen Wang, Zhengchao Tu, Yulai Zhou, Ke Ding, Yong Xu
2016 Feb
Journal of Medicinal Chemistry
Low dose triptolide reverses chemoresistance in adult acute lymphoblastic leukemia cells via reactive oxygen species generation and DNA damage response disruption
Zhao H, Shi P, Deng M, Jiang Z, Li Y, Kannappan V, Wang W, Peng Li, Xu B
2016 Dec
Oncotarget
Effective elimination of adult B-lineage acute lymphoblastic leukemia by disulfiram/copper complex in vitro and in vivo in patient-derived xenograft models
Manman Deng, Zhiwu Jiang, Yin Li, Yong Zhou, Jie Li, Xiangmeng Wang,Yao Yao, Weiguang Wang, Peng Li, Bing Xu
2016 Dec
oncotarget
Molecular basis for the genome engagement by Sox proteins
Linlin Hou, Yogesh Srivastava, Ralf Jauch
2016 Aug
Seminars in Cell & Developmental Biology
Lysine-specific histonedemethylase 1 inhibition promotes reprogramming by facilitating the expression of exogenous transcriptional factors and metabolic switch
Hao Sun, Lining Liang1, Yuan Li, Chengqian Feng, Lingyu Li, Yixin Zhang, Songwei He,Duanqing Pei1, Yunqian Guo,Hui Zheng
2016 Aug
Scientific Reports
Identification and characterization of rabbit ROSA26 for gene knock-in and stable reporter gene expression
Dongshan Yang, Jun Song, Jifeng Zhang, Jie Xu, Tianqing Zhu, Zhong Wang, Liangxue Lai,Y. Eugene Chen
2016 Apr
Scientific Reports
Efficient Generation of Myostatin Gene Mutated Rabbit by CRISPR/Cas9
Qingyan Lv, Lin Yuan, Jichao Deng, Mao Chen, Yong Wang, Jian Zeng, Zhanjun Li,Liangxue Lai
2016 Apr
Scientific RepoRts
Genetically humanized pigs exclusively expressing human insulin are generated through custom endonuclease-mediated seamless engineering
Yi Yang, Kepin Wang, Han Wu, Qin Jin, Degong Ruan, Zhen Ouyang, Bentian Zhao, Zhaoming Liu, Yu Zhao, Quanjun Zhang, Nana Fan, Qishuai Liu, Shimei Guo,Lei Bu, Yong Fan, Xiaofang Sun, Xiaoping Li, Liangxue Lai
2016 Apr
Journal of Molecular Cell Biology
Transcriptional Control of Somatic Cell Reprogramming
Yan Xu, Meng Zhang, Wenjuan Li, Xihua Zhu, Xichen Bao, Baoming Qin, Andrew P. Hutchins, Miguel A. Esteban
2016 Apr
Trends in Cell Biology
Biochemical and Structural Insights into the Aminotransferase CrmG in Caerulomycin Biosynthesis
Yiguang Zhu, Jinxin Xu, Xiangui Mei, Zhan Feng, Liping Zhang, Qingbo Zhang,Guangtao Zhang, Weiming Zhu, Jinsong Liu,Changsheng zhang
2016 Apr
ACS Chemical Biology
Unprecedented reactions: from epichlorohydrin to epoxyglycidyl substituted divinyl ether and its conversion into epoxyglycidyl propargyl ether
Yiwu Yao, Zheng Li, Yatao Qiu, Jinhong Bai, Jinyue Su, Dayong Zhang, Sheng Jiang
2015 Sep
Scientific Reports
An Enantioselective Synthesis of Spirobilactams through CopperCatalyzed Intramolecular Double N-Arylation and Phase Separation
Jianguang Liu,Yingying Tian,Jialing Shi,Shasha Zhang,Qian Cai
2015 Sep
Angewandte Chemie-International Edition
Discovery of Novel Class I Histone Deacetylase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities
Yiwu Yao, Zhengchao Tu, Chenzhong Liao, Zhen Wang, Shang Li, Hequan Yao, Zheng Li, Sheng Jiang
2015 Oct
Journal of Medicinal Chemistry
Copper-Promoted Cycloaddition of α-Methylenyl Isocyanides with Benzothiazoles: Tunable Access to Benzo[d]imidazothiazoles
Jian Wang, Jing Li,Qiang Zhu
2015 Nov
Organic Letters
SOXE transcription factors form selective dimers on non-compact DNA motifs through multifaceted interactions between dimerization and high-mobility group domains
Yong-Heng Huang, Aleksander Jankowski, Kathryn S. E. Cheah, Shyam Prabhakar, Ralf Jauch
2015 May
Scientific Reports
Total synthesis of (+)-gelsemine via an organocatalytic Diels-Alder approach
Xiaoming Chen, Shengguo Duan, Cheng Tao, Hongbin Zhai, Fayang G. Qiu.
2015 May
Nature Communications
Copper-Catalyzed Trifluoromethylalkynylationof Isocyanides
Jian Lei, Xiaoxing Wu,Qiang Zhu.
2015 May
Organic Letters
ANGPTL7 regulates the expansion and repopulation of human hematopoietic stem and progenitor cells
Yiren Xiao, Zhiwu Jiang, Yin Li, Wei Ye, Bei Jia, Minjie Zhang, Yan Xu, Donghai Wu, Liangxue Lai, Yaoyu Chen, Yingjun Chang, Xiaojun Huang, Hudan Liu, Guoliang Qing, Pentao Liu, Yangqiu Li, Bing Xu, Mei Zhong, Yao Yao, Duanqing Pei, Peng Li.
2015 May
Haematologica
Valproic Acid-Induced Hepatotoxicity in Alpers Syndrome Is Associated With Mitochondrial Permeability Transition Pore Opening-Dependent Apoptotic Sensitivity in an Induced Pluripotent Stem Cell Model
Shengbiao Li, Jingyi Guo, Zhongfu Ying, Shen Chen,Liang Yang, Keshi Chen, Qi Long, Dajiang Qin, Duanqing Pei,Xingguo Liu.
2015 May
Hepatology
Genomic analysis of LPS-stimulated myeloid cells identifies a common pro-inflammatory response but divergent IL-10 anti-inflammatory responses
Andrew Paul Hutchins,Yoshiko Takahashi,Diego Miranda-Saavedra.
2015 Mar
Scientific Reports
Aminopalladation-Triggered Carbene Insertion Reaction:Synthesis of 2-(1H-Indol-3-yl)acetates
Ziwei Hu, Shuang Luo,Qiang Zhu.
2015 Mar
Advanced Synthesis & Catalysis
Generation of CRISPR/Cas9-mediated gene-targeted pigs via somatic cell nuclear transfer
Xiaoqing Zhou, Jige Xin, Nana Fan, Qingjian Zou, Jiao Huang, Zhen Ouyang, Yu Zhao, Bentian Zhao, Zhaoming Liu, Sisi Lai, Xiaoling Yi, Lin Guo, Miguel A. Esteban, Yangzhi Zeng, Huaqiang Yang, Liangxue Lai
2015 Mar
Cellular and Molecular Life Sciences
Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming
Yasong Wu,Yuan Li,Hui Zhang,Yinghua Huang,Ping Zhao,Yujia Tang,Xiaohui Qiu,Yue Ying,Wen Li,Su Ni,Meng Zhang,Longqi Liu,Yan Xu,Qiang Zhuang,Zhiwei Luo,Christina Benda,Hong Song, Baohua Liu, Liangxue Lai, Xingguo Liu, Hung-Fat Tse,Xichen Bao, Wai-Yee Chan,Miguel A. Esteban, Baoming Qin,Duanqing Pei.
2015 Jun
Nature Cell Biology
Copper-Catalyzed Intramolecular Desymmetric Aryl C-O Coupling for the Enantioselective Construction of Chiral Dihydrobenzofurans and Dihydrobenzopyrans
Wenqiang Yang,Yangyuan Liu, Shasha Zhang,Qian Cai.
2015 Jul
Angewandte Chemie-International Edition
The oncogene c-Jun impedes somatic cell reprogramming
Jing Liu, Qingkai Han, Tianran Peng,Meixiu Peng, BeiWei, Dongwei Li, XiaoshanWang,Shengyong Yu, Jiaqi Yang, Shangtao Cao, Kaimeng Huang, Andrew Paul Hutchins, He Liu,Junqi Kuang, Zhiwei Zhou, Jing Chen, HaoyuWu, Lin Guo, Yongqiang Chen, You Chen, Xuejia Li,HonglingWu, Baojian Liao,Wei He, Hong Song, Hongjie Yao, Guangjin Pan, Jiekai Chen,Duanqing Pei.
2015 Jul
Nature Cell Biology
Mitochondrial fusion provides an 'initial metabolic complementation' controlled by mtDNA
Liang Yang, Qi Long, Jinglei Liu, Haite Tang, Yuxing Li, Feixiang Bao, Dajiang Qin, Duanqing Pei, Xingguo Liu.
2015 Jul
Cellular and Molecular Life Sciences
The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpGmethylation at pluripotency gene promoters
Xichen Bao, Haitao Wu, Xihua Zhu, Xiangpeng Guo, Andrew P Hutchins, Zhiwei Luo,Hong Song, Yongqiang Chen, Keyu Lai, Menghui Yin, Lingxiao Xu, Liang Zhou, Jiekai Chen,Dongye Wang, Baoming Qin, Jon Frampton, Hung-Fat Tse, Duanqing Pei, Huating Wang,Biliang Zhang, Miguel A Esteban
2015 Jan
Cell Research
Structural basis of AMPK regulation by adenine nucleotides and glycogen
Xiaodan Li, Lili Wang, X Edward Zhou, Jiyuan Ke, Parker W de Waal, Xin Gu, M H Eileen Tan, Dongye Wang, Donghai Wu, H Eric Xu, Karsten Melcher.
2015 Jan
Cell Research