Scientific Publications
Title Aouther Year Kw
Defined, serum/feeder-free conditions for expansion and drug screening of primary B-acute lymphoblastic leukemia
Zhiwu Jiang, Di Wu, Wei Ye, Jianyu Weng, Peilong Lai, Pengcheng Shi, Xutao Guo, Guohua Huang, Qiuhua Deng, Yanlai Tang, Hongyu Zhao, Shuzhong Cui, Simiao Lin, Suna Wang, Baiheng Li, Qiting Wu, Yangqiu Li, Pentao Liu, Duanqing Pei, Xin Du, Yao Yao,Peng Li
2017 Nov;
Oncotarget
Kdm2b Regulates Somatic Reprogramming through Variant PRC1 Complex-Dependent Function
Zhiwei Zhou,Xuejie Yang,Jiangping He,Jing Liu,Fang Wu,Shengyong Yu,Yuting Liu,Runxia Lin,He Liu,Yuanbin Cui,Chunhua Zhou,Xiaoshan Wang,Jian Wu,Shangtao Cao,Lin Guo,Lihui Lin,Tao Wang,Xiaozhong Peng,Boqing Qiang,Andrew P.Hutchins,Duanqing Pei,Jiekai Chen
2017 Nov;
Cell Reports
Passive DNA demethylation preferentially up-regulates pluripotency-related genes and facilitates the generation of induced pluripotent stem cells
Songwei He, Hao Sun, Lilong Lin, Yixin Zhang, Jinlong Chen, Lining Liang, Yuan Li,Mengdan Zhang, Xiao Yang, Xiaoshan Wang, Fuhui Wang, Feiyan Zhu, Jiekai Chen,Duanqing Pei,Hui Zheng
2017 Nov;
Journal of Biological Chemistry
A sequential EMT-MET mechanism drives the differentiation of human embryonic stem cells towards hepatocytes
Qiuhong Li, Andrew P. Hutchins, Yong Chen, Shengbiao Li, Yongli Shan, Baojian Liao, Dejin Zheng,Xi Shi, Yinxiong Li, Wai-Yee Chan, Guangjin Pan, Shicheng Wei, Xiaodong Shu, Duanqing Pei
2017 May;
Nature Communications
Pentafluorosulfanyl-Substituted Benzopyran Analogues As New Cyclooxygenase-2 Inhibitors with Excellent Pharmacokinetics and Efficacy in Blocking Inflammation
Yanmei Zhang,Yican Wang,Chuang He,Xiaorong Liu,Yongzhi Lu,Tingting Chen,Qiong Pan,Jingfang Xiong,Miaoqin She,Zhengchao Tu,Xiaochu Qin, Minke Li,Micky D. Tortorella,John J.Talley
2017 May;
Journal of Medicinal Chemistry
Current status and perspectives of patient-derived xenograft models in cancer research
Yunxin Lai, Xinru Wei, Shouheng Lin, Le Qin, Lin Cheng,Peng Li
2017 May;
Journal of Hematology & Oncology
Models of global gene expression define major domains of cell type and tissue identity
Andrew P. Hutchins, Zhongzhou Yang, Yuhao Li, Fangfang He, Xiuling Fu,Xiaoshan Wang, Dongwei Li, Kairong Liu, Jiangping He, Yong Wang, Jiekai Chen,Miguel A. Esteban,Duanqing Pei
2017 Mar;
Nucleic Acids Research
Fumarylacetoacetate Hydrolase Knock-out Rabbit Model for Hereditary Tyrosinemia Type 1
Li Li, Quanjun Zhang, Huaqiang Yang, Qingjian Zou, Chengdan Lai, Fei Jiang, Ping Zhaoa,Zhiwei Luo, Jiayin Yang, Qian Chen, Yan Wang, Philip N. Newsome, Jon Frampton, Patrick H. Maxwell,Wenjuan Lia, Shuhan Chen, Dongye Wang, Tak-Shing Siu, Sidney Tam, Hung-Fat Tse,Baoming Qin, Xichen Baoa, Miguel A. Esteban, Liangxue Lai
2017 Mar;
Journal of Biological Chemistry
Generation of Human Liver Chimeric Mice with Hepatocytes from Familial Hypercholesterolemia Induced Pluripotent Stem Cells
Jiayin Yang, Yu Wang, Ting Zhou, Lai-Yung Wong, Xiao-Yu Tian, Xueyu Hong, Wing-Hon Lai, Ka-Wing Au, Rui Wei, Yuqing Liu, Lai-Hung Cheng, Guichan Liang, Zhijian Huang, Wenxia Fan, Ping Zhao, Xiwei Wang, David P. Iba?ez, Zhiwei Luo, Yingying Li, Xiaofen Zhong, Shuhan Chen, Dongye Wang, Li Li, Liangxue Lai, Baoming Qin, Xichen Bao, Andrew P. Hutchins, Chung-Wah Siu, Yu Huang, Esteban MA,Hung-Fat Tse
2017 Mar;
Stem Cell Reports
AXL is not essential for Zika virus infection in the mouse brain
Feng Li,Pei-Rong Wang,Lin-Bing Qu,Chang-Hua Yi,Fu-Chun Zhang,Xiao-Ping Tang,Li-Guo Zhang,Ling Chen
2017 Mar;
Emerging Microbes & Infections
Copper-catalyzed regioselective 1,2-thioamidation of alkenes
Dengke Li,Tingting Mao, Jinbo Huang,Qiang Zhu
2017 Mar;
Chemical Communications
Molecular basis for the genome engagement by Sox proteins
Linlin Hou, Yogesh Srivastava, Ralf Jauch
2017 Mar;
Seminars in Cell & Developmental Biology
Suppressing P16Ink4a and P14ARF pathways overcomes apoptosis in individualized human embryonic stem cells
Wenqian Wang, Yanling Zhu, Ke Huang, Yongli Shan, Juan Du, Xiaoya Dong, Ping Ma, Pengfei Wu, Jian Zhang, Wenhao Huang, Tian Zhang, Baojian Liao, Deyang Yao, Guangjin Pan,Jiajun Liu
2017 Mar;
FASEB Journal
Incorporation of a hinge domain improves the expansion of chimeric antigen receptor T cells
Le Qin, Yunxin Lai, Ruocong Zhao, Xinru Wei, Jianyu Weng, Peilong Lai, Baiheng Li,Simiao Lin, Suna Wang, Qiting Wu, Qiubin Liang, Yangqiu Li, Xuchao Zhang, Yilong Wu, Pentao Liu,Yao Yao, Duanqing Pei, Xin Du,Peng Li
2017 Mar;
Journal of Hematology & Oncology
Mutation of the Sp1 binding site in the 5' flanking region of SRY causes sex reversal in rabbits
Yuning Song, Tingjun Liu, Yong Wang, Jichao Deng, Mao Chen, Lin Yuan, Yi Lu, Yuxin Xu, Haobin Yao, Zhanjun Li,Liangxue Lai
2017 Jun;
Oncotarget
Seroprevalence of neutralizing antibodies against adenovirus type 14 and 55 in healthy adults in Southern China
Xuehua Zheng,, Xia Rong, Ying Feng, Xikui Sun, Liang Li, Qian Wang, Min Wang, Wenkuan Liu, Chufang Li, Yiyu Yang, Rong Zhou, Jiahai Lu, Liqiang Feng,Ling Chen
2017 Jun;
Emerging Microbes & Infections
Palladium-Catalyzed Enantioselective C(sp(2))-H lmidoylation by Desymmetrization
Jian Wang,De-Wei Gao,Jinbo Huang,Shi Tang,Zhuang Xiong,Huaanzi Hu,Shu-Li You,Qiang Zhu
2017 Jun;
ACS Catalysis
Denitrogenative Imidoyl Radical Cyclization: Synthesis of 2-Substituted Benzoimidazoles from 1-Azido-2-isocyanoarenes.
Dengke Li, Tingting Mao, Jinbo Huang,Qiang Zhu
2017 Jun;
Organic Letters
2-Oxo-3, 4-dihydropyrimido[4, 5-d]pyrimidinyl derivatives as new irreversible pan fibroblast growth factor receptor (FGFR) inhibitors
Xueqiang Li,Christopher P.Guise,Rana Taghipouran,Yuliana Yosaatmadja,Amir Ashoorzadeh,Woo-Kyong Paik,Christopher J.Squire,Shuang Jiang ,Jinfeng Luo,Yong Xu,Zheng-Chao Tu,Xiaoyun Lu,Xiaomei Ren,Adam V.Patterson,Jeff B.Smaill,Ke Ding
2017 Jul;
European Journal of Medicinal Chemistry
Generation of Hoxc13 knockout pigs recapitulates human ectodermal dysplasia-9
Kai Han, Liuping Liang, Li Li, Zhen Ouyang, Bentian Zhao, Qi Wang,Zhaoming Liu, Yu Zhao, Xiaoshuai Ren, Fei Jiang, Chengdan Lai,Kepin Wang, Sen Yan, Liang Huang, Lin Guo, Kang Zeng,Liangxue Lai,Nana Fan
2017 Jan;
Human Molecular Genetics
A one-pot synthesis of [1,2,3]triazolo[1,5-a]quinoxalines from 1-azido-2-isocyanoarenes with high bond-forming efficiency
Dengke Li, Tingting Mao, Jinbo Huang,Qiang Zhu
2017 Jan;
Chemical Communications
Brown Adipogenic Reprogramming Induced by a Small Molecule
Nie Baoming,Nie Tao,Hui Xiaoyan,Gu Ping,Mao Liufeng,Li Kuai,Yuan Ran,Zheng Jiashun,Wang Haixia,Li Ke,Tang Shibing,Zhang Yu,Xu Tao,Xu Aimin,Wu Donghai,Ding Shen
2017 Jan;
Cell Reports
Anti-GPC3-CAR T Cells Suppress the Growth of Tumor Cells in Patient-Derived Xenografts of Hepatocellular Carcinoma
Zhiwu Jiang, Xiaofeng Jiang, Suimin Chen, Yunxin Lai, Xinru Wei,Baiheng Li, Simiao Lin, Suna Wang, Qiting Wu, Qiubin Liang, Qifa Liu,Muyun Peng, Fenglei Yu, Jianyu Weng, Xin Du, Duanqing Pei, Pentao Liu,Yao Yao, Ping Xue,Peng Li
2017 Jan;
Frontiers In Immunology
Organocatalytic Friedel-Crafts Alkylation/Lactonization Reaction of Naphthols with 3-Trifluoroethylidene Oxindoles: The Asymmetric Synthesis of Dihydrocoumarins
Yun-Long Zhao, Qin-Xin Lou, Long-Sheng Wang, Wen-Hui Hu,Jun-Ling Zhao
2017 Jan
Angewandte Chemie-International Edition
Quantitative profiling of selective Sox/POU pairing on hundreds of sequences in parallel by Coop-seq
Yiming K. Chang, Yogesh Srivastava, Caizhen Hu, Adam Joyce, Xiaoxiao Yang, Zheng Zuo, James J. Havranek, Gary D. Stormo, Ralf Jauch
2017 Jan
Nucleic Acids Research
Changing POU dimerization preferences converts Oct6 into a pluripotency inducer
Stepan Jerabek, Calista KL Ng, Guangming Wu, Marcos J Arauzo-Bravo, Kee-Pyo Kim,Daniel Esch, Vikas Malik, Yanpu Chen, Sergiy Velychko, Caitlin M MacCarthy,Xiaoxiao Yang, Vlad Cojocaru, Hans R Sch?ler,Ralf Jauch
2017 Feb;
EMBO Reports
Visualization and Quantification of Browning Using a Ucp1-2A-Luciferase Knock-in Mouse Model
Mao Liufeng,Nie Baoming,Nie Tao,Hui Xiaoyan,Gao Xuefei,Lin Xiaoliang,Liu Xin,Xu Yong,Tang Xiaofeng,Yuan Ran,Li Kuai,Li Peng,Ding Ke,Wang Yu,Xu Aimin,Fei Jian,Han Weiping,Liu Pentao,Madsen Lise,Kristiansen Karsten,Zhou Zhiguang,Ding Sheng,Wu Donghai
2017 Feb;
Diabetes
PSCA and MUC1 in non-small-cell lung cancer as targets of chimeric antigen receptor T cells
Xinru Wei, Yunxin Lai, Jin Li, Le Qin, Youdi Xu, Ruocong Zhao, Baiheng Li,Simiao Lin, Suna Wang, Qiting Wu, Qiubin Liang, Muyun Peng, Fenglei Yu,Yangqiu Li, Xuchao Zhang, Yilong Wu, Pentao Liu, Duanqing Pei, Yao Yao,Peng Li
2017 Feb
OncoImmunology
CD215+ Myeloid Cells Respond to Interleukin 15 Stimulation and Promote Tumor Progression
Shouheng Lin, Guohua Huang, Yiren Xiao, Wei Sun, Yuchuan Jiang, Qiuhua Deng, Muyun Peng, Xinru Wei, Wei Ye, Baiheng Li, Simiao Lin, Suna Wang, Qiting Wu, Qiubin Liang, Yangqiu Li, Xuchao Zhang, Yilong Wu, Pentao Liu, Duanqing Pei, Fenglei Yu, Zhesheng Wen, Yao Yao, Donghai Wu,Peng Li
2017 Dec;
Frontier in Immunology
Chromatin Accessibility Dynamics during iPSC Reprogramming
Dongwei Li,Jing Liu,Xuejie Yang,Chunhua Zhou,Jing Guo,Chuman Wu,Yue Qin,Lin Guo,Jiangping He,Shenyong Yu,He Liu,Xiaoshan Wang,Fang Wu, Junqi Kuang,Andrew P.Hutchins, Jiekai Chen,Duanqing Pe
2017 Dec;