-
Nov 20, 2015The novel role of TRPV2 in promoting the cytotoxicity of H2O2-mediated oxidative stress in human hepatoma cells have been discovered by GIBH scientistsCarcinogenesis is a multistep complicated process in which oxidative stress is considered as an important risk factor for cancer occurrence and progression. DNA and cells of the human body are constantly exposed to exogenous or endogenou...
-
Nov 04, 2015GIBH scientists have generated the world’s first gene-target dogs using CRISPR/Cas9 systemDogs exhibit close similarities to humans in terms of metabolic,physiological, and anatomical characteristics, and thus are ideal genetic and clinical models to study human diseases. Gene target technology is a powerful tool to create ne...
-
Nov 04, 2015GIBH scientists have generated the world’s first gene-target dogs using CRISPR/Cas9 systemDogs exhibit close similarities to humans in terms of metabolic,physiological, and anatomical characteristics, and thus are ideal genetic and clinical models to study human diseases. Gene target technology is a powerful tool to create ne...
-
Apr 20, 2015The role of ANGPTL7 in hematopoietic stem and progenitor cells has been identified by GIBH scientistsThe autologous-allogeneic hematopoietic cell transplantation has been developed for decades, and numerous attempts have been made to expand the HSCs population in vitro and in vivo. Agiopoietin-like proteins belong to a 7-member family o...
-
Apr 20, 2015The role of ANGPTL7 in hematopoietic stem and progenitor cells has been identified by GIBH scientistsThe autologous-allogeneic hematopoietic cell transplantation has been developed for decades, and numerous attempts have been made to expand the HSCs population in vitro and in vivo. Agiopoietin-like proteins belong to a 7-member family o...
-
Apr 14, 2015GIBH Scientists Discovered that KLF4 can act as an important negative regulator in T-cell acute lymphoblastic leukemiaThe research group led by Prof Peng Li at GIBH has recently identified that KLF4 can inhibit T-ALL progression by suppressing the expression of T-cell associated genes. KLF4, also known as GKLF (gut KLF), is a member of the KLF zinc fing...