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Mar 04, 2014Generation of human Neuronal restricted progenitors by GIBH scientistsRecently, a research group led by Prof. Liangxue Lai has successfully transdifferentiated human fetal fibroblasts into human Neuronal Restricted Progenitors (hiNRPs). The hiNRPs can proliferate and differentiate specifically into termina...
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Nov 14, 2013GIBH Scientists Found the Important Role of Hepatocyte Nuclear Factor 4α (HNF4α) in the Regulation of Assembly and Secretion of Hepatitis C VirusHepatitis C virus (HCV) is a major cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma worldwide. The assembly and secretion of HCV are closely correlated with the very-low-density lipoprotein (VLDL) secretory pathw...
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Nov 14, 2013GIBH Scientists Found the Important Role of Hepatocyte Nuclear Factor 4α (HNF4α) in the Regulation of Assembly and Secretion of Hepatitis C VirusHepatitis C virus (HCV) is a major cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma worldwide. The assembly and secretion of HCV are closely correlated with the very-low-density lipoprotein (VLDL) secretory pathw...
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Oct 09, 2013Study revealed the important role of regulatory B cells in control of malaria-induced immunopathologyCerebral malaria (CM) is a neurological syndrome often occurring in human severe malaria. Although CM is known as an immunopathology in brain tissue mediated by excessive pro-inflammatory cytokines, the immunoregulatory mechanism is poor...
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Oct 09, 2013Study revealed the important role of regulatory B cells in control of malaria-induced immunopathologyCerebral malaria (CM) is a neurological syndrome often occurring in human severe malaria. Although CM is known as an immunopathology in brain tissue mediated by excessive pro-inflammatory cytokines, the immunoregulatory mechanism is poor...
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Jul 29, 2013The Scientists in GIBH Created Immune-deficient Rabbits by Using TALEN TechnologyRecently, a research group led by Prof. Liangxue Lai and Duanqing Pei has successfully applied transcription activator-like effector nucleases (TALENs) to rabbit gene targeting and established a high-efficiency technique platform for spe...