Scientific Publications
Title Aouther Year Kw
Pyrido[2, 3-d]pyrimidin-7(8H)-ones as new selective orally bioavailable Threonine Tyrosine Kinase (TTK) inhibitors
Minhao Huang, Yongjun Huang, Jing Guo, Lei Yu, Yu Chang, Xiaolu Wang, Jinfeng Luo, Yanhui Huang, Zhengchao Tu, Xiaoyun Lu, Yong Xu, Zhimin Zhang, Zhang Zhang, Ke Ding
2021 Feb;
European journal of medicinal chemistry
Author Correction: Phase separation drives the self-assembly of mitochondrial nucleoids for transcriptional modulation
Qi Long, Yanshuang Zhou, Hao Wu, Shiwei Du, Mingli Hu, Juntao Qi, Wei Li, Jingyi Guo, Yi Wu, Liang Yang, Ge Xiang, Liang Wang, Shouhua Ye, Jiayuan Wen , Heng Mao, Junwei Wang, Hui Zhao, Wai-Yee Chan, Jinsong Liu, Yonglong Chen , Pilong Li, Xingguo Liu
2021 Dec;
NATURE STRUCTURAL & MOLECULAR BIOLOGY
AP?1 activity is?a?major barrier of?human somatic cell reprogramming
Yuting Liu, Jiangping He, Ruhai Chen, He Liu, Jocelyn Chen, Yujian Liu, Bo Wang, Lin Guo, Duanqing Pei, Jie Wang, Jing Liu, Jiekai Chen
2021 Aug;
Cellular and Molecular Life Sciences
A recombinant selective drug-resistant M. bovis BCG enhances the bactericidal activity of a second-line anti-tuberculosis regimen
Chiwala G, Liu Z, Mugweru JN, Wang B, Khan SA, Bate PNN, Yusuf B, Hameed HMA, Fang C, Tan Y, Guan P, Hu J, Tan S, Liu J, Zhong N, Zhang T
2021 Aug;
Biomedicine & Pharmacotherapy
Recapitulative haematopoietic development of human pluripotent stem cells in the absence of exogenous haematopoietic cytokines
Elena S Philonenko, Ying Tan, Cuihua Wang, Baoyun Zhang, Zahir Shah, Jianguang Zhang, Hanif Ullah, Sergei L Kiselev, Maria A Lagarkova, Dandan Li, Yong Dai,Igor M Samokhvalov
2021 Aug;
Journal of cellular and molecular medicine
Nitric oxide-dependent electron transport chain inhibition by the cytochrome bc1 inhibitor and pretomanid combination kills Mycobacterium tuberculosis
Sheng Zeng, Jingran Zhang, Mingwei Sun, Xiaofei Zhang, Gregory M Cook,Tianyu Zhang
2021 Aug;
Antimicrobial Agents and Chemotherapy
SAGE1: a potential target antigen for lung cancer T-cell immunotherapy
Li Y, Zhang Y, Yu X, Liu Q, Gong H, Chen AA, Zheng H, Zhong S
2021 Aug;
Molecular cancer therapeutics
SAA1/TLR2 axis directs chemotactic migration of hepatic stellate cells responding to injury
Anteneh Getachew, Nasir Abbas, Kai You, Zhen Yang, Muzammal Hussain,Xinping Huang, Ziqi Cheng, Shenglin Tan, Jiawang Tao, Xiaorui Yu, Yan Chen,Fan Yang, Tingcai Pan, Yingying Xu, Guosheng Xu, Yuanqi Zhuang, FeiMa Wu,Yinxiong Li
2021 Apr;
iScience
Rapid visualized assessment of drug efficacy in live mice with a selectable marker-free autoluminescent Klebsiella pneumoniae
Xirong Tian, Yamin Gao, Shuai Wang, H M Adnan Hameed, Wei Yu, Cuiting Fang, Jingran Zhang, Yaoju Tan, Zhizhong Cao , Ping Guan, Jinxing Hu , Jianxiong Liu, Nanshan Zhong, Tianyu Zhang
2021 Apr;
BIOSENSORS & BIOELECTRONICS
A General Strategy for the Construction of Calyciphylline A-Type Alkaloids: Divergent Total Syntheses of (-)-Daphenylline and (-)-Himalensine A
Bingyang Wang, Bo Xu, Wen Xun, Yiming Guo , Jing Zhang, Fayang G Qiu
2021 Apr;
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Mesenchymal Stem Cells Suppress Leukemia via Macrophage-Mediated Functional Restoration of Bone Marrow Microenvironment
Chengxiang Xia,Tongjie Wang,Hui Cheng,Yong Dong,Qitong Weng,Guohuan Sun,Peiqing Zhou,Kaitao Wang, Xiaofei Liu,Yang Geng,Shihui Ma,Sha Hao,Ling Xu,Yuxian Guan,Juan Du,Xin Du,Yangqiu Li,Xiaofan Zhu,Yufang Shi,Sheng Xu,Demin Wang,Tao Cheng,Jinyong Wang
2020 Sep;
Leukemia
Mitochondrial DNA mutation exacerbates female reproductive aging via impairment of the NADH/NAD + redox
Liang Yang,Xiaobing Lin,Haite Tang,Yuting Fan,Sheng Zeng,Lei Jia,Yukun Li,Yanan Shi,Shujing He,Hao Wang,Zhijuan Hu,Xiao Gong,Xiaoyan Liang,Yi Yang,Xingguo Liu
2020 Sep;
Aging Cell
ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems
Jingke Xie,Xingyun Huang,Xia Wang,Shixue Gou,Yanhui Liang,Fangbing Chen,Nan Li,Zhen Ouyang,Quanjun Zhang,Weikai Ge,Qin Jin,Hui Shi,Zhenpeng Zhuang,Xiaozhu Zhao,Meng Lian,Jiaowei Wang,Yinghua Ye,Longquan Quan,Han Wu,Kepin Wang,Liangxue Lai
2020 Sep;
BMC Biology
NUP98-HOXA10hd fusion protein sustains multi-lineage haematopoiesis of lineage-committed progenitors in transplant setting
Yong Dong,Kaitao Wang,Qitong Weng,Tongjie Wang,Peiqing Zhou,Xiaofei Liu,Yang Geng,Lijuan Liu,Hongling Wu,Jinyong Wang,Juan Du
2020 Sep;
Cell Proliferation
Systematic screening of CTCF binding partners identifies that BHLHE40 regulates CTCF genome-wide distribution and long-range chromatin interactions
Gongcheng Hu,Xiaotao Dong,Shixin Gong,Yawei Song,Andrew P Hutchins,Hongjie Yao
2020 Sep;
Nucleic Acids Research
YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways
Jiadong Liu,Mingwei Gao,Shuyang Xu,Yaping Chen,Kaixin Wu,He Liu,Jie Wang,Xuejie Yang,Junwei Wang,Weiwei Liu,Xichen Bao,Jiekai Chen
2020 Sep;
Cell Reports
Perspectives on Somatic Reprogramming: Spotlighting Epigenetic Regulation and Cellular Heterogeneity
Jiekai Chen
2020 Oct;
Current Opinion in Genetics & Development
JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency
Yinghua Huang,Hui Zhang,Lulu Wang,Chuanqing Tang,Xiaogan Qin,Xinyu Wu,Meifang Pan,Yujia Tang,Zhongzhou Yang,Isaac A Babarinde,Runxia Lin,Guanyu Ji,Yiwei Lai,Xueting Xu,Jianbin Su,Xue Wen,Takashi Satoh, Tanveer Ahmed,Vikas Malik,Carl Ward,Giacomo Volpe,Lin Guo,Jinlong Chen,Li Sun,Yingying Li,Xiaofen Huang, Xichen Bao,Fei Gao,Baohua Liu,Hui Zheng,Ralf Jauch,Liangxue Lai,Guangjin Pan,Jiekai Chen,Giuseppe Testa,Shizuo Akira,Jifan Hu,Duanqing Pe,Andrew P Hutchin,Miguel A Esteban,Baoming Qin
2020 Oct;
Nature Communication
Rapid,serial,non-invasive quantification of Pseudomonas aeruginosa in live mice with a selectable marker-free autoluminescent strain
Shuai Wang,Wei Yu,Zhiyong Liu,Xiaoyin Cai,Sheng Zeng,Jingran Zhang,Yamin Gao,Yaoju Tan,Zhizhong Cao,Lingmin Guo,H.M.Adnan Hameed,Shahzad Akbar Khan,Zafran Khan,Xirong Tian,Cuiting Fang,Md Mahmudul Islam,Sanjeep Sapkota,Ping Guan,Jinxing Hu,Jianxiong Liu,Nanshan Zhong,Tianyu Zhang
2020 Oct;
Biosensors & Bioelectronics
Tandem [5 + 2]/[4 + 2] Cycloadditions To Construct the [6-7-6] Tricyclic Skeleton of Icetexane Diterpenes: Total Synthesis of Euolutchuol E, Przewalskine E and Brussonol
Jing Zhang,Yehua Jin,Fayang G Qiu
2020 Oct;
Organic letters
Sustainable Approach to Azaheterocyclic Acetamides by Decarboxylative Aminoformylation
Zhenxing Zhang,Chunqi Jia,Xiangtao Kong,Muzammal Hussain,Zhenyu Liu,Wanqing Liang,Ling Jiang,Hao Jiang,Junyan Ma
2020 Nov;
ACS Sustainable Chemistry & Engineering
Pd-Catalyzed Domino Imidoylation/Heck/C(sp2)-H Cyclization: Isocyanide Relay Strategy toward Tricyclic-Fused Heterocycles Containing an All-Carbon Quaternary Center
Fan Teng,Yan Peng,Xilong Wang,Weiming Hu,Huaanzi Hu,Yimiao He,Shuang Luo,Qiang Zhu
2020 Nov;
Organic Letters
Generation of rat blood vasculature and hematopoietic cells in rat-mouse chimeras by blastocyst complementation
Xiaomin Wang,Hui Shi,Juanjuan Zhou,Qingjian Zou,Quanjun Zhang,Shixue Gou,Pengfei Chen,Lisha Mou,Nana Fan,Yangyang Suo,Zhen Ouyang,Chengdan Lai,Quanmei Yan,Liangxue Lai
2020 May;
Journal of Genetics and Genomics
Morphine and Naloxone Facilitate Neural Stem Cells Proliferation via a TET1-Dependent and Receptor-Independent Pathway
Lining Liang,Jinlong Chen,Yuan Li,Xiaowei Lai,Hao Sun,Changpeng Li,Mengdan Zhang,Tingting Yang,Fei Meng,Ping-Yee Law,Horace H. Loh,Hui Zheng
2020 Mar;
Cell Reports
Topology-dependent, bifurcated mitochondrial quality control under starvation
Yanshuang Zhou,Qi Long,Hao Wu,Wei Li,Juntao Qi,Yi Wu,Ge Xiang,Haite Tang,Liang Yang,Keshi Chen,Linpeng Li,Feixiang Bao,Heying Li,Yaofeng Wang,Min Li,Xingguo Liu
2020 Mar;
Autophagy
BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling
Shengyong Yu,Chunhua Zhou,Shangtao Cao,Jiangping He,Baomei Cai,Kaixin Wu,Yue Qin,Xingnan Huang,Lizhan Xiao,Jing Ye,Shuyang Xu,Wenxiu Xie,Junqi Kuang,Shilong Chu,Jing Guo,He Liu,Wei Pang,Lin Guo,Mengying Zeng,Xiaoshan Wang,Rongping Luo,Chen Li,Guoqing Zhao,Bo Wang,Linlin Wu,Jiekai Chen,Jing Liu,Duanqing Pei
2020 Jun;
Nature Cell Biology
R-loops coordinate with SOX2 in regulating reprogramming to pluripotency
Yaoyi Li,Yawei Song,Wei Xu,Qin Li,Xinxiu Wang,Kuan Li,Juehan Wang,Zicong Liu,Sergiy Velychko,Rong Ye,Qing Xia,Lei Wang,Rong Guo,Xiaotao Dong,Zhikai Zheng,Yushuang Dai,Haojie Li,Mingze Yao,Yuanchao Xue, Hans R. Sch?ler,Qianwen Sun,Hongjie Yao
2020 Jun;
Science Advances
β-Catenin safeguards the ground state of mouse pluripotency by strengthening the robustness of the transcriptional apparatus
Meng Zhang,Yiwei Lai,Vladislav Krupalnik,Pengcheng Guo,Xiangpeng Guo,Jianguo Zhou,Yan Xu,Zhijun Yu,Longqi Liu,Ao Jiang,Wenjuan Li,Mazid Md Abdul,Gang Ma,Na Li,Xiuling Fu,Yuan Lv,Mengling Jiang,Muqddas Tariq,Shahzina Kanwal,Hao Liu,Xueting Xu,Hui Zhang,Yinghua Huang,Lulu Wang,Shuhan Chen,Isaac A Babarinde,Zhiwei Luo,Dongye Wang,Tiantian Zhou,Carl Ward,Minghui He,David P Iba?ez,Yunpan Li,Jiajian Zhou, Jie Yuan,Yayan Feng,Karthik Arumugam,Umberto Di Vicino,Xichen Bao,Guangming Wu,Axel Schambach,Huating Wang,Hao Sun,Fei Gao,Baoming Qin,Andrew P Hutchins,Bradley W Doble,Christine Hartmann, Maria Pia Cosma,Yan Qin,Guo-Liang Xu,Runsheng Chen,Giacomo Volpe,Liang Chen,Jacob H Hanna,Miguel A Esteban
2020 Jul;
Science Advances
An ultrasensitive and specific point-of-care CRISPR/Cas12 based lateral flow biosensor for the rapid detection of nucleic acids
Omar Mukama,Jinghua Wu,Zhiyuan Li,Qiongxin Liang,Zhijian Yi,Xuewen Lu,Yujie Liu,Yumei Liu,Muzammal Hussain,Gaelle Guiewi Makafe,Jiaxin Liu,Ning Xu,Lingwen Zeng
2020 Jul;
Biosensors and Bioelectronics
JMJD3 and UTX determine fidelity and lineage specification of human neural progenitor cells
Yongli Shan,Yanqi Zhang,Yuan Zhao,Tianyu Wang,Jingyuan Zhang,Jiao Yao,Ning Ma,Zechuan Liang,Wenhao Huang,Ke Huang,Tian Zhang,Zhenghui Su,Qianyu Chen,Yanling Zhu,Chuman Wu,Tiancheng Zhou,Wei Sun,Yanxing Wei,Cong Zhang,Chenxu Li,Shuquan Su,Baojian Liao,Mei Zhong,Xiaofen Zhong,Jinfu Nie,Duanqing Pei,Guangjin Pan
2020 Jan;
Nature Communications