Scientific Publications
Title Aouther Year Kw
BMP4 drives primed to na?ve transition through PGC-like state
Shengyong Yu, Chunhua Zhou, Jiangping He, Zhaokai Yao, Xingnan Huang, Bowen Rong, Hong Zhu, Shijie Wang, Shuyan Chen, Xialian Wang, Baomei Cai, Guoqing Zhao, Yuhan Chen, Lizhan Xiao, He Liu, Yue Qin, Jing Guo, Haokaifeng Wu , Zhen Zhang, Man Zhang, Xiaoyang Zhao, Fei Lan, Yixuan Wang, Jiekai Chen, Shangtao Cao, Duanqing Pei, Jing Liu
2022
Nature Communications
Multiplexed base editing through Cas12a variant-mediated cytosine and adenine base editors
Fangbing Chen,Meng Lian,Bingxiu Ma,Shixue Gou,Xian Luo,Kaiming Yang,Hui Shi,Jingke Xie,Weika Ge,Zhen Ouyang,Chengdan Lai,Nan Li,Quanjun Zhang,Qin Jin,Yanhui Liang,Tao Chen,Jiaowei Wang,Xiaozhu Zhao,Lei Li,Manya Yu,Yinghua Ye,Kepin Wang,Han Wu& Liangxue Lai
2022
Communications Biology
From immune equilibrium to immunodynamics
Xiaoping Chen
2022
Frontiers in Microbiology
Analysis of B Cell Receptor Repertoires Reveals Key Signatures of the Systemic B Cell Response after SARS-CoV-2 Infection
Yudi Zhang, Qihong Yan, Kun Luo, Ping He, Ruitian Hou, Xinwei Zhao, Qian Wang, Haisu Yi, Huan Liang, Yijun Deng, Fengyu Hu, Feng Li, Xinglong Liu, Ying Feng, Pingchao Li, Linbing Qu, Zhaoming Chen, Qiang Pan-Hammarstr?m, Liqiang Feng,Xuefeng Niu,Ling Chen
2022
Journal of Virology
Discovery of the first examples of threonine tyrosine kinase PROTAC degraders
Jibu Lu, Yongjun Huang, Jing Huang, Rui He, Minhao Huang, Xiaoyun Lu, Yong Xu, Fengtao Zhou, Zhang Zhang, Ke Ding.
2022
Journal of Medicinal Chemistry
AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patterns
Yanhui Liang,Jingke Xie,Quanjun Zhang, Xiaomin Wang1,Shixue Gou1,Lihui Lin1,Tao Chen,Weikai Ge1,Zhenpeng Zhuang,Meng Lian,Fangbing Chen1, Nan Li,ZhenOuyang,Chengdan Lai,Xiaoyi Liu1,Lei Li1,Yinghua Ye,HanWu,Kepin Wang,Liangxue Lai
2022
Nucleic Acids Research
Structure- Based Discovery and Optimization of Furo[3,2-c]pyridin-4(5H)-one Derivatives as Potent and Second Bromodomain (BD2)-Selective Bromo and Extra Terminal Domain (BET) Inhibitors
Junhua Li#, Cheng Zhang#, Hongrui Xu, Chao Wang, Ruibo Dong, Hui Shen, Xiaoxi Zhuang, Xiaoshan Chen, Qiu Li, Jibu Lu, Maofeng Zhang, Xishan Wu, Kerry M. Loomes, Yulai Zhou, Yan Zhang, Jinsong Liu, and Yong Xu*
2022
Journal of Medicinal Chemistry
COVID-19-associated liver injury: Clinical characteristics, pathophysiological mechanisms and treatment management.
Penghui Li, Ying Liu, Ziqi Cheng, Xiaorui Yu, Yinxiong Li
2022
Biomed Pharmacother
Palladium-Catalyzed Modular Synthesis of Enantioenriched Pyridohelicenes through Double Imidoylative Cyclization
Ting Yu, Zhong-Qiu Li, Jing Li, Sidi Cheng, Jiali Xu, Jun Huang, Yu-Wu Zhong*, Shuang Luo* and Qiang Zhu*
2022
ACS Catalysis
Thermal stress involved in TRPV2 promotes tumorigenesis through the pathways of HSP70/27 and PI3K/Akt/mTOR in esophageal squamous cell carcinoma
Rongqi Huang, Shuai Li, Chao Tian, Peng Zhou, Huifang Zhao, Wei Xie, Jie Xiao, Ling Wang, Jean de Dieu Habimana, Zuoxian Lin, Yuchen Yang, Na Cheng and Zhiyuan Li
2022
British Journal of Cancer
Rolling back of human pluripotent stem cells to an 8-cell embryo-like stage
Mazid, M.A., Ward, C., Luo, Z., Liu, C., Li, Y., Lai, Y., Wu, L., Li, J., Jia, W., Jiang, Y., Liu, H., Fu, L., Yang, Y., Ibanez, D.P., Lai, J., Wei, X., An, J., Guo, P., Yuan, Y., Deng, Q., Wang, Y., Liu, Y., Gao, F., Wang, J., Zaman, S., Qin, B., Wu, G., Maxwell, P.H., Xu, X., Liu, L., Li, W., and Esteban, M.A.
2022
Nature
Harnessing enhanced CRISPR/Cas12a trans-cleavage activity with extended reporters and reductants for early diagnosis of Helicobacter pylori, the causative agent of peptic ulcers and stomach cancer
Jean de Dieu Habimana, Omar Mukama, Guiquan Chen, Mengjun Chen, Obed Boadi Amissah, Lin Wang, Yujie Liu, Yirong Sun, Amy L. Li, Sihao Deng, Jufang Huang, Xiao-xin Yan, Theobard Rutaganda, Dieudonne Mutangana, Lin-Ping Wu, Rongqi Huang ,Zhiyuan Li
2022
Biosensors and Bioelectronics
Generating functional cells through enhanced interspecies chimerism with human pluripotent stem cells
Yanling Zhu, Zhishuai Zhang, Nana Fan, Ke Huang, Hao Li, Jiaming Gu, Quanjun Zhang, Zhen Ouyang, Tian Zhang, Jun Tang, Yanqi Zhang, Yangyang Suo, Chengdan Lai, Jiaowei Wang, Junwei Wang, Yongli Shan, Mingquan Wang, Qianyu Chen, Tiancheng Zhou, Liangxue Lai, Guangjin Pan
2022
Stem Cell Reports
Protocol for isolation and proteostatic analysis of sub-populations of spermatogenic cells in mouse
Qianxing Zou, Lele Yang, Huayu Qi
2022
STAR Protocols
Ectopic expression of meiotic cohesin generates chromosomeinstability in cancer cell line
Abdelhalim Boukaba, Jian Liu, Carl Ward, Qiongfang Wu, Alexei Arnaoutov, Jierong Liang, Elena M Pugacheva, Mary Dasso, Victor Lobanenkov, Miguel Esteban, Alexander V Strunnikov
2022
Proceedings of the National Academy of Sciences of the United States of America
Generation of a genetically modified pig model with CREBRF R457Q variant
Yingying Li,Hai Wang,Huangyao Chen,Yuan Liao,Shixue Gou,Quanmei Yan,Zhenpeng Zhuang,Hao Li,Jiaowei Wang,Yangyang Suo,Ting Lan,Yang Liu,Yu Zhao,Qingjian Zou,Tao Nie,Xiaoyan Hui,Liangxue Lai,Donghai Wu,Nana Fan
2022
FASEB Journal
Transcription factor EB-mediated mesenchymal stem cell therapy induces autophagy and alleviates spinocerebellar ataxia type 3 defects in neuronal cells model
Xiaobo Han, Jean de Dieu Habimana, Amy L. Li, Rongqi Huang, Omar Mukama, Weiyue Deng, Ling Wang, Yuying Zhang, Wei Wang, Sihao Deng, Kexin Peng, Bin Ni, Shusheng Zhang, Jufang Huang, Xiao-xin Yan and Zhiyuan Li.
2022
Cell Death & Disease
Shared IGHV1-69-encoded neutralizing antibodies contribute to the emergence of L452R substitution in SARS-CoV-2 variants
Qihong Yan, Ruitian Hou, Xiaohan Huang, Yanjun Zhang, Ping He, Yudi Zhang, Banghui Liu, Qian Wang, Haiyue Rao, Xianying Chen, Xinwei Zhao, Xuefeng Niu, Jincun Zhao, Xiaoli Xiong, Ling Chen
2022
Emerging Microbes & Infections
Origin and Reversion of Omicron Core Mutations in the Evolution of SARS-CoV-2 Genomes
Xin-Wei Zhao, Luyao Qin, Xiao Ding, Yudi Zhang, Xuefeng Niu, Feng Gao , Taijiao Jiang and Ling Chen.
2022
Viruses
CTCF functions as an insulator for somatic genes and a chromatin accessibility and structural regulator for pluripotency genes during reprogramming.
Song Y#, Liang Z#, Zhang J#, Hu G#, Wang J, Li Y, Guo R, Dong X, Babarinde IA, Ping W, Sheng Y, Li H, Chen Z, Gao M, Chen Y, Zhang MQ, Hutchins AP, Fu X* and Yao H*
2022
Cell Reports
Shared IGHV1-69-encoded neutralizing antibodies contribute to the emergence of L452R substitution in SARS-CoV-2 variants
Qihong Yan , Ruitian Hou , Xiaohan Huang , Yanjun Zhang , Ping He , Yudi Zhang , Banghui Liu , Qian Wang , Haiyue Rao , Xianying Chen , Xinwei Zhao , Xuefeng Niu , Jincun Zhao , Xiaoli Xiong , Ling Chen
2022
Emerging Microbes & Infections
Substrate-induced dimerization of elaiophylin glycosyltransferase reveals a novel self-activating form of glycosyltransferase for symmetric glycosylation glycosyltransferase reveals a novel self-activating form of glycosyltransferase for symmetric glycosylation
Tingting Xu, Qingqing Gan, Qiang Liu, Ruidong Chen, Xuhui Zhen,Changsheng Zhang and Jinsong Liu
2022
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY
Analysis of B Cell Receptor Repertoires Reveals Key Signatures of the Systemic B Cell Response after SARS-CoV-2 Infection
Yudi Zhang, Qihong Yan, Kun Luo, Ping He, Ruitian Hou, Xinwei Zhao, Qian Wang, Haisu Yi, Huan Liang, Yijun Deng, Fengyu Hu, Feng Li, Xinglong Liu, Ying Feng, Pingchao Li, Linbing Qu, Zhaoming Chen, Qiang Pan-Hammarstr?m, Liqiang Feng,Xuefeng Niu,Ling Chen
2022
Journal of Virology
Discovery, optimization and evaluation of 1-(indolin-1-yl)ethan-1- ones as novel selective TRIM24/BRPF1 bromodomain inhibitors
Qiuping Xiang,Guolong Luo,Cheng Zhang,Qingqing Hua,Chao Wang,Tianbang Wu,c,Hongrui Xu,Jiankan gHu,Xiaoxi Zhuang,Maofeng Zhang,Shuang Wu,Jinxin Xu,YanZhang,Jinsong Liu,Yong Xu
2022
European Journal of Medicinal Chemistry
Nuclear localization of mitochondrial TCA cycle enzymes modulates pluripotency via histone acetylation
Wei Li, Qi Long , Hao Wu, Yanshuang Zhou , Lifan Duan, Hao Yuan , Yingzhe Ding , Yile Huang , Yi Wu , Jinyu Huang, Delong Liu, Baodan Chen, Jian Zhang , Juntao Qi, Shiwei Du, Linpeng Li , Yang Liu, Zifeng Ruan, Zihuang Liu, Zichao Liu, Yifan Zhao , Jianghuan Lu, Junwei Wang, Wai-Yee Chan & Xingguo Liu.
2022
Nature Communications
Parallel Kinetic Resolution through Palladium-Catalyzed Enantioselective Cycloimidoylation: En Route to Divergent N-Heterocycles Bearing a Quaternary Stereogenic Center
Xilong Wang, Yu Luo, Jing Li, Chaoqin Wang, Qianwen Liu, Yimiao He, Shuang Luo* and Qiang Zhu
2022
ACS Catalysis
Sterilizing Effects of Novel Regimens Containing TB47, Clofazimine and Linezolid in a Murine Model of Tuberculosis
Wei Yu, Yusuf Buhari, Shuai Wang, Xirong Tian, H M Adnan Hameed, Zhili Lu, Gift Chiwala, Md Shah Alam, Gregory M Cook, Dmitry A Maslov, Nanshan Zhong, Tianyu Zhang
2021 Sep;
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Capture of the newly transcribed RNA interactome using click chemistry
Wang D, Yin M, Qin B, Zhang B, Bao X, Esteban MA
2021 Oct;
Nature Protocols
Generation of permanent neonatal diabetes mellitus dogs with glucokinase point mutations through base editing
Wang X, Liang Y, Zhao J, Li Y, Gou S, Zheng M, Zhou J, Zhang Q, Mi J, Lai L
2021 Oct;
Cell Discovery
Organocatalytic Asymmetric Arylation of p_x001e_Quinone Phosphonates: A Green Access to Biaryl Monophosphorus Ligands
Guodong Sun, Zhuofei Deng, Zhonghua Luo, Zhongqing Wang,Jiancun Zhang
2021 Oct;
Organic Letters