New Gene that Might Regulate the Formation of Eukaryotic Cells’ Intracellular Membranous System Discovered by Researcher of GIBH

Eukaryotic cells maintain a sophisticated network of intracellular membranous system to ensure the proper distribution and compartmentalization of cellular proteins critical for diverse functions such as cell division or cell-cell communication. Yet, little is known about the mechanism that regulates the homeostasis of this system. However, QIN Baoming, a researcher from Dr. PEI Duanqing’s group of GIBH discovered that the expression of SNX10 induced the formation of giant vacuoles in mammalian cells. Experiment results suggested that SNX10 activity might be involved in the regulation of endosome homeostasis. The discovery may provide inspirations for the study in this area. A paper entitled “Sorting Nexin 10 Induces Giant Vacuoles in Mammalian Cells” reporting this discovery is to be published on the Journal of Biological Chemistry of December 1st, 2006 of.

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The Journal of Biological Chemistry is owned and published by the American Society of Biochemistry and Molecular Biology, Inc. The JOURNAL is an internationally well-known publication in the field of biological and biomedical studies. Articles in this journal are based on original researches that make novel and important contributions to the understanding of any area of biochemistry or molecular biology. This is the first time that the work done by investigators of our institute is published in this journal. Additionally, the picture attached to the article was selected to be the cover figure of the issue.