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Apr 14, 2025Researchers discover a new mode of "mito-meet-to-mitochondria" (mtMET) in the regulation of stem cell fate by mitochondrial stressOn April 9, 2025, a research team led by LIU Xingguo from the Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, published a paper titled "The mitochondrial unfolded protein response inhibits pluripotency acquis...Mitochondria play a crucial role in the acquisition of pluripotency and the determination of cell fate. The mitochondrial unfolded protein response (UPRmt) is an important retrograde regulatory pathway from mitochondria to the nucleus. I... -
Apr 03, 2025Researchers Unveil a Detailed Molecular Map of Mouse Lung DevelopmentA recent study conducted by the Guangzhou Institutes of Biomedicine and Health,Chinese Academy of Sciences (GIBH, CAS), in collaboration with the University of Science and Technology of China, Guangzhou Medical University,Guangzhou Natio... -
Feb 18, 2025The research team of GIBH discovered the target gene Lhx2 in hepatic stellate cells regulating liver regeneration and fibrosisRecently, the research teams of WANG Jie and LI Yinxiong from the Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences (GIBH, CAS), in collaboration with YUAN Shengxian's team from the Eastern Hepatobiliary Surgery... -
Feb 17, 2025Researchers Unlock Guinea Pig Epiblast Stem CellsSince the advent of pluripotent stem cell (PSC) technology, researchers have continually advanced methods to refine efficiency, improve safety, and uncover novel biological insights. While guinea pigs have historically played a vital rol... -
Feb 17, 2025International Collaboration Uncovered Potential Therapeutic Strategies for Solid Tumors by Targeting UHRF1 for DNA DemethylationA recent study, led by Dr. KONG Xiangqian, Dr. LIU Jinsong, and Dr. WU Linping's labs at the Guangzhou Institutes of Biomedicine and Health (GIBH), Chinese Academy of Sciences (CAS), in collaboration with Dr. Stephen Baylin's group at Th... -
Jan 26, 2025Researchers developed a novel method for SALL4-mediated somatic cell reprogrammingRecently, Prof. LIU Jing from Guangzhou Institutes of Biomedicine and Health (GIBH), Chinese Academy of Sciences, in collaboration with Prof. LIAO Baojian of the Fifth Affiliated Hospital of Guangzhou Medical University, published an art...Recently, Prof. LIU Jing from Guangzhou Institutes of Biomedicine and Health (GIBH), Chinese Academy of Sciences, in collaboration with Prof. LIAO Baojian of the Fifth Affiliated Hospital of Guangzhou Medical University, published an art...