Principal Investigator
Principal Investigator
Name:Jing Liu
Professional:Principle Investigator
Email:
Address:Kaiyuan Dadao 190,510530,Guangzhou,China
Study/Work Experience

2018.01 – now Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences,China/Researcher Follow

2013.01 – 2017.12 Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences,China/Associate Professor

2007.09 – 2012.06 Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences,China/Ph.D

2003.09 – 2007.06 Hubei University, China/Bechelor

Research Areas

Cell fate determination, Somatic Cell Reprogramming, Embryonic Stem Cell

Academic Performance
Representative Papers

 1、Yu, S., C. Zhou, S. Cao, J. He, B. Cai, K. Wu, Y. Qin, X. Huang, L. Xiao, J. Ye, S. Xu, W. Xie, J. Kuang, S. Chu, J. Guo, H. Liu, W. Pang, L. Guo, M. Zeng, X. Wang, R. Luo, C. Li, G. Zhao, B. Wang, L. Wu, J. Chen, J. Liu and D. Pei (2020). "BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling." Nat Cell Biol 22(6): 651-662.

 2、Wang, B., L. Wu, D. Li, Y. Liu, J. Guo, C. Li, Y. Yao, Y. Wang, G. Zhao, X. Wang, M. Fu, H. Liu, S. Cao, C. Wu, S. Yu, C. Zhou, Y. Qin, J. Kuang, J. Ming, S. Chu, X. Yang, P. Zhu, G. Pan, J. Chen, J. Liu and D. Pei (2019). "Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Jdp2-Jhdm1b-Mkk6-Glis1-Nanog-Essrb-Sall4." Cell Rep 27(12): 3473-3485 e3475.

3、Cao, S., S. Yu, D. Li, J. Ye, X. Yang, C. Li, X. Wang, Y. Mai, Y. Qin, J. Wu, J. He, C. Zhou, H. Liu, B. Zhao, X. Shu, C. Wu, R. Chen, W. Chan, G. Pan, J. Chen, J. Liu and D. Pei (2018). "Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency." Cell Stem Cell 22(4): 529-542 e525.

4、Wang, B., D. Li, J. Chen, J. Liu and D. Pei (2018). "Mouse embryonic stem cells resist c-Jun induced differentiation when in suspension." Cell Regen 7(1): 16-21. 

5、Li, D., J. Liu, X. Yang, C. Zhou, J. Guo, C. Wu, Y. Qin, L. Guo, J. He, S. Yu, H. Liu, X. Wang, F. Wu, J. Kuang, A. P. Hutchins, J. Chen and D. Pei (2017). "Chromatin Accessibility Dynamics during iPSC Reprogramming." Cell Stem Cell 21(6): 819-833 e816. 

6、Cao, S., S. Yu, Y. Chen, X. Wang, C. Zhou, Y. Liu, J. Kuang, H. Liu, D. Li, J. Ye, Y. Qin, S. Chu, L. Wu, L. Guo, Y. Li, X. Shu, J. Chen, J. Liu and D. Pei (2017). "Chemical reprogramming of mouse embryonic and adult fibroblast into endoderm lineage." J Biol Chem 292(46): 19122-19132.

7、Liu, J., Q. Han, T. Peng, M. Peng, B. Wei, D. Li, X. Wang, S. Yu, J. Yang, S. Cao, K. Huang, A. P. Hutchins, H. Liu, J. Kuang, Z. Zhou, J. Chen, H. Wu, L. Guo, Y. Chen, Y. Chen, X. Li, H. Wu, B. Liao, W. He, H. Song, H. Yao, G. Pan, J. Chen and D. Pei (2015). "The oncogene c-Jun impedes somatic cell reprogramming." Nat Cell Biol 17(7): 856-867. 

8、Ouyang, J., W. Yu, J. Liu, N. Zhang, L. Florens, J. Chen, H. Liu, M. Washburn, D. Pei and T. Xie (2015). "Cyclin-dependent kinase-mediated Sox2 phosphorylation enhances the ability of Sox2 to establish the pluripotent state." J Biol Chem 290(37): 22782-22794. 

9、Chen, J., J. Liu, J. Yang, Y. Chen, J. Chen, S. Ni, H. Song, L. Zeng, K. Ding and D. Pei (2011). "BMPs functionally replace Klf4 and support efficient reprogramming of mouse fibroblasts by Oct4 alone." Cell Res 21(1): 205-212. 

10、Chen, J., J. Liu, Y. Chen, J. Yang, J. Chen, H. Liu, X. Zhao, K. Mo, H. Song, L. Guo, S. Chu, D. Wang, K. Ding and D. Pei (2011). "Rational optimization of reprogramming culture conditions for the generation of induced pluripotent stem cells with ultra-high efficiency and fast kinetics." Cell Res 21(6): 884-894. 

11、Chen, J., J. Liu, Q. Han, D. Qin, J. Xu, Y. Chen, J. Yang, H. Song, D. Yang, M. Peng, W. He, R. Li, H. Wang, Y. Gan, K. Ding, L. Zeng, L. Lai, M. A. Esteban and D. Pei (2010). "Towards an optimized culture medium for the generation of mouse induced pluripotent stem cells." J Biol Chem 285(40): 31066-31072.