Faculty
LUO Shuang
Title:
Subject:
Email:luo_shuang@gibh.ac.cn
Address:190 Kaiyuan Avenue, Guangzhou Science Park, Huangpu District, Guangzhou
Study/Work Experience
Research Areas

Prof. Luo is currently a doctoral supervisor at GIBH. His research primarily focuses on organic chemistry, medicinal chemistry, and computational chemistry. Since 2009, he has published over 30 papers as the first or corresponding author in well-known domestic and international journals, including JACS, ACIE, CCS Chem., and ACS Catal., with a total impact factor (IF) exceeding 220. His work has been cited over 1,000 times. He has served as the principal investigator for three National Natural Science Foundation projects (two general projects and one youth science fund project) and three provincial-level projects. He was selected as a member of the Youth Innovation Promotion Association of the CAS in 2015. He also serves as a reviewer for international journals such as Nat. Commun., Chem. Commun., and Adv. Synth. Catal., and as an evaluation expert for the National Natural Science Foundation and the Guangdong Provincial Department of Science and Technology.


Patents
1.Qiang Zhu, Yu Luo, Shuang Luo, Xilong Wang, Yan Peng, Chaoqin Wang. Chiral dibenz[e,g][1,4]diazocine ligands and their preparation methods. Chinese patent No. 202110022559.4

Academic Performance

1.The Youth Innovation Promotion Association of CAS, 2015

Representative Papers

1.Xilong Wang, Jiali Xu, Yu Luo*, Yuanyu Wang, Jun Huang*, Qiang Zhu* and Shuang Luo*, DFT-Assisted Atroposelective Construction of Indole-Fused N-Heteroaromatic Frameworks through Palladium-Catalyzed C–H Imidoylation. ACS Catal., 2025, 15, 201–210.


2.Sidi Cheng, Ting Yu, Jing Li*, Yingxiang Liang, Shuang Luo* and Qiang Zhu*, Copper/ Chiral Phosphoric Acid-Catalyzed Intramolecular Reduc-tive Isocyanide-Alkene (1+2) Cycloaddition: Enantioselective Construction of 2-Azabicyclo[3.1.0]hexanes. J. Am. Chem. Soc, 2024, 146, 7956–7962.


3.Ting Yu, Sidi Cheng, Yu Luo, Jing Li, Yingxiang Liang, Shuang Luo*, and Qiang Zhu*, Immobilizing Stereogenic Nitrogen Center in Doubly Fused Triarylamines through Palladium-Catalyzed Asymmetric C-H Activation/Seven-Membered-Ring Formation. ACS Catal., 2023, 13, 9688–9694.


4.Yu Luo, Xilong Wang, Weiming Hu, Yan Peng, Chaoqin Wang, Ting Yu, Sidi Cheng, Jing Li, Yimiao He, Chunfang Gan, Shuang Luo* and Qiang Zhu*, Inherently Chiral 6,7-Diphenyldibenzo[e,g][1,4]diazocine: Enantioselective Synthesis and Application as a Ligand Platform. CCS Chem., 2023, 5, 982-993.


5.Xilong Wang, Yu Luo, Jing Li, Chaoqin Wang, Qianwen Liu, Yimiao He, Shuang Luo* and Qiang Zhu*, Parallel Kinetic Resolution through Palladium-Catalyzed Enantioselective Cycloimidoylation: En Route to Divergent N-Heterocycles Bearing a Quaternary Stereogenic Center. ACS Catal., 2022, 12, 14918-14925.


6.Ting Yu, Zhong-Qiu Li, Jing Li, Sidi Cheng, Jiali Xu, Jun Huang, Yu-Wu Zhong*, Shuang Luo* and Qiang Zhu*, Palladium-Catalyzed Modular Synthesis of Enantioenriched Pyridohelicenes through Double Imidoylative Cyclization. ACS Catal., 2022, 12, 13034-13041.


7.Sidi Cheng, Yu Luo, Ting Yu, Jing Li, Chunfang Gan, Shuang Luo* and Qiang Zhu*, Palladium-Catalyzed Four-Component Cascade Imidoyl-Carbamoylation of Unactivated Alkenes. ACS Catal., 2022, 12, 837-845.


8.Yu Luo, Sidi Cheng, Yan Peng, Xilong Wang, Jing Li, Chunfang Gan, Shuang Luo* and Qiang Zhu*, A New Saddle-Shaped Aza Analog of Tetraphenylene: Atroposelective Synthesis and Application as a Chiral Acylating Reagent. CCS Chem., 2022, 4, 2897-2905.


9.Fan Teng, Ting Yu, Yan Peng, Weiming Hu, Huaanzi Hu, Yimiao He, Shuang Luo* and Qiang Zhu*, Palladium-Catalyzed Atroposelective Coupling-Cyclization of 2-Isocyanobenzamides to Construct Axially Chiral 2-Aryl- and 2,3-Diarylquinazolinones. J. Am. Chem. Soc., 2021, 143, 2722-2728.


10.Huaanzi Hu, Fan Teng, Jian Liu, Weiming Hu, Shuang Luo* and Qiang Zhu*, Enantioselective Synthesis of 2-Oxindole Spirofused Lactones and Lactams by Heck/Carbonylative Cylization Sequences: Method Development and Applications. Angew. Chem. Int. Ed., 2019, 58, 9225-9229.