FENG Liqiang--Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences

Faculty

FENG Liqiang

Title：Principle Investigator

Subject：

Email：feng_liqiang@gibh.ac.cn

Address：Kaiyuan Dadao 190,510530,Guangzhou,China

Study/Work Experience

2018 – now	Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences/ Investigator
2013 – 2017	Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences / Associate Investigator
2010 – 2012	Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences / Research Assistant
2005 – 2010	Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences / Ph.D
2001 – 2005	School of the Environment, Nanjing University/ B.S

Research Areas

Vaccines against emerging respiratory viruses, Genetic vectors based on human adenovirus

Academic Performance

Dr. Feng’s group is focused on vaccines against respiratory infectious diseases and genetic vectors based on human adenoviruses. Dr. Feng and his team have been developing several novel vaccine strategies using HAdV vectors, for the prevention of emerging viruses such as Ebola and Zika virus. He has published more than 10 peer reviewed papers in international journals including “Emerging Microbes & Infections”, “NPJ Vaccines”, “Journal of Virology”, and “Virology”. Dr. Feng has been undertaking several national and local research programs, such as the grants from National Natural Science Foundation of China (No. 31470892), National Key Research and Development Project (No. 2016YFC1200900), National Science and Technology Major Projects of China (No. 2017ZX10204401003), and Guangzhou Health Care and Cooperative Innovation Major Project. Dr. Feng was selected as the member of CAS Youth Innovation Promotion Association in 2014, and was awarded the Pearl River S&T Nova Program of Guangzhou.

Representative Papers

1. Xinglong Liu^#, Zhengfeng Li^#, Xiao Li^#, Xiaoyan Zhang,Yali Zheng, Wan Su, Ying Feng, Yutong Liu, Weixuan Wu, Xikui Sun, Nana Wang, Xianmiao Ye, Zhichao Zhou, Wenkuan Liu, Jun He, Wei Wang*, Linbing Qu*, Rong Zhou*, Ling Chen*, Liqiang Feng*. Neutralizing monoclonal antibodies protect against human adenovirus type 55 infection in transgenic mice and tree shrews.Emerg Microbes Infect. 2024, 13(1):2307513.

2. Pingchao Li^#* , Qian Wang^#, Yizi He^#, Chenchen Yang^#, Zhengyuan Zhang, Zijian Liu, Bo Liu, Li Yin, Yilan Cui, Peiyu Hu, Yichu Liu, Pingqian Zheng, Wei Wang, Linbing Qu, Caijun Sun, Suhua Guan, Liqiang Feng*, Ling Chen*. Booster vaccination is required to elicit and maintain COVID-19 vaccine-induced immunity in SIV-infected macaques. Emerg Microbes Infect. 2023, 12(1):e2136538.

3. Jinlin Wang^#, Tao Shu^#, Weiqi Deng, Yali Zheng, Min Liao, Xianmiao Ye, Lujie Han, Ping He, Xuehua Zheng, Ting Li, Ying Feng, Fengyu Hu, Pingchao Li, Caijun Sun, Ling Chen*, Feng Li*, Liqiang Feng*.Mucosal Priming with a Recombinant Influenza A Virus-Vectored Vaccine Elicits T-Cell and Antibody Responses to HIV-1 in Mice. Journal of Virology. 2021, 95(12):e00059-21.

4. Xianmiao Ye^#,Xinglong Liu^#,Tao Shu,Weiqi Deng,Min Liao,Yali Zheng,Xuehua Zheng,Xiaoyan Zhang,Ting Li,Wenxia Fan,Linbing Qu,Ling Chen*, Feng Li*, Liqiang Feng*.A Live-Attenuated Zika Virus Vaccine with High Production Capacity Confers Effective Protection in Neonatal Mice.J Virol. 2021, 95(14):e0038321.

5. Lei Yu^#,Xinglong Liu^#,Xianmiao Ye^#,Wan Su,Xiaoyan Zhang,Weiqi Deng,Jia Luo,Mengrong Xiang,Wenjing Guo,Shengnan Zhang,Wei Xu,Qihong Yan,Qian Wang,Yilan Cui, Caixia Wu,Wenjing Guo,Xuefeng Niu,Fuchun Zhang,Chunliang Lei,Linbing Qu,Ling Chen*,Liqiang Feng*.Monoclonal Antibodies against Zika Virus NS1 Protein Confer Protection via Fc γ Receptor-Dependent and -Independent Pathways.mBio. 2021, 12(1):e03179-20.

6. Liqiang Feng^#, Qian Wang^#, Chao Shan^#, Chenchen Yang, Ying Feng, Jia Wu, Xiaolin Liu, Yiwu Zhou, Rendi Jiang, Peiyu Hu, Xinglong Liu, Fan Zhang, Pingchao Li, Xuefeng Niu, Yichu Liu, Xuehua Zheng, Jia Luo, Jing Sun, Yingying Gu, Bo Liu, Yongcun Xu, Chufang Li, Weiqi Pan, Jincun Zhao, Changwen Ke, Xinwen Chen, Tao Xu, Nanshan Zhong, Suhua Guan*, Zhiming Yuan*, Ling Chen*. An adenovirus-vectored COVID-19 vaccine confers protection from SARS-COV-2 challenge in rhesus macaques. Nature Communications. 2020, 11(1):4207.

7. Ying Feng^#, Changhua Yi^#, Xinglong Liu^#, Linbing Qu, Wan Su, Tao Shu, Xuehua Zheng, Xianmiao Ye, Jia Luo, Mingli Hao, Xikui Sun, Liang Li, Xiaolin Liu, Chenchen Yang, Suhua Guan, Ling Chen*, Liqiang Feng*. Human desmoglein-2 and human CD46 mediate HAdV55 infection but human desmoglein-2 plays the major roles. Journal of Virology. 2020, 94(17): e00747-20.