News--Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences

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MSC-Mediated Mitochondrial Transfer Restores Mitochondrial DNA and Function in Neural Progenitor Cells of Leber's Hereditary Optic Neuropathy

Researchersled byProf. LIU Xingguo fromGuangzhou Institutes of Biomedicine and Healthof Chinese Academy of Sciences and Prof. ZHANG QingjiongfromZhongshan Ophthalmic Centerhave discovered that that MSC-mediated mitochondrial transfer can effectively restore mitochondrial DNA (mtDNA) and improve mitochondrial function in neural progenitor cells derived from patients with Lebe...

Mechanisms of Aging Associated Protein Translation Deficiency Discovered

The teams led by Prof. WANG Tao and Prof. WANG Jie from GIBH collaborated to identify novel mechanisms for regulating aging. The finding was published in Nature Communications with the title "Perturbation of METTL1-mediated tRNA N7-methylguanosine modification induces senescence and aging". The study discovered that METTL1/WDR4-mediated tRNA-m7G methylation was essential in ...

Researchers Make New Progress in Studying Automated Monoclonal Lineage Cells Selecting Technology

Despite the broad prospects for the application of lineage-specific cells in regenerative medicine, traditional methods for obtaining monoclonal lineage cells through manual manipulation are time-consuming, labor-intensive, and generally inefficient. Furthermore, these methods cannot acquire monoclonal lineage cells in a label-free, enzyme-free, and non-invasive manner. Alth...

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Structural snapshots reveal how the plant KCS6-CER2 complex drives very-long-chain fatty acid elongation

Researchers have developed two PROTAC degraders which target BRD9 for combating malignancies

Researchers Uncover How ERDRP-0519 Differentially Targets Morbillivirus and Henipavirus Polymerases, Enabling Structure-Guided Inhibitor Optimization

Researchers reveal a cell-fate "rheostat" governing somatic reprogramming

GIBH Collaborates to Develop Selective DNMT1 Inhibitors for Hypomethylating Agent-Resistant Acute Myeloid Leukemia

Researchers develop a mitochondrial transplantation approach for mitochondrial and degenerative diseases

Researchers reveal organ-specific vascular development in embryonic mouse

Researchers Develop a Safer and More Efficient mTOR Inhibitor

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【xinhua】Chinese scientists grow humanized kidneys in pig embryos

【xinhua】Chinese scientists grow humanized kidneys in pig embryos

【Science】Early-stage human kidneys grown in pigs for first time

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