In recent years, Dr.Wu’s research team has focused on the following projects: 1) Generation of a mouse model for quantitative study of browning of white adipocytes, which can be used to directly look for the new browning factors of white adipocytes both in vivo and in vitro. This work was published in Diabetes 2017; 2) Discovery of a natural compound, Formononetin, in Astragalus membranaceus,  that acts as a partial agonist of PPARgamma to promote browning of white adipocytes and resist obesity induced by high-fat diet in mice. This work was published on British Journal of Pharmacology. 3) Discovery of a small molecule drug, Bexarotene, to enhance the formation of brown adipocytes and resist obesity by using a brown adipocyte trans-differentiation screening platform. This work was published on Cell Reports in 2017. Overall, Dr. Wu has published 27 professional papers as a corresponding author since his return to China in 2004. He was invited to attend international conferences and presented 12 seminars and has applied for 17 patents.